Boron agent delivery platforms based on natural products for boron neutron capture therapy

R Kawasaki, Y Miura, N Kono, S Fujita… - …, 2024 - Wiley Online Library
Boron neutron capture therapy (BNCT) is one of the most promising modalities for cancer
treatment due to its minimal invasiveness. Although two types of boron agents are clinically …

Immunodetection of Poorly Soluble Substances: Limitations and Their Overcoming

B AN, H OD, K NS, Z AV, D BB - Critical Reviews in Analytical …, 2024 - Taylor & Francis
Immunoassays based on the specific antigen—antibody interactions are efficient tools to
detect various compounds and estimate their content. Usually, these assays are …

“On‐Off” Switching of Functional Guest Molecules via Exchange of Natural Product Solubilizing Agents

R Kawasaki, A Ikeda - ChemBioChem, 2023 - Wiley Online Library
For the development of delivery systems, the solubilization of hydrophobic guest molecules
in water is an important yet challenging task. This can be achieved by preparing stable …

Formation of Poly‐L‐Lysine–Porphyrin Derivative Complex Exhibiting Diminished Dark Toxicity in Aqueous Solutions and High Photodynamic Activity

Y Egashira, N Kono, N Tarutani, K Katagiri, S Hino… - ChemBioChem - Wiley Online Library
Poly‐L‐lysine (PLL) displays a high solubilizing ability for hydrophobic guest molecules, and
when in complexes with guest molecules, it exhibits a high intracellular uptake. However, its …