The regenerative and immunomodulatory characteristics of mesenchymal stem cells (MSCs)
make them attractive in the treatment of many diseases. Although they have shown …

Diabetes mellitus—whether driven by insulin deficiency or insulin resistance—causes major
alterations in muscle metabolism. These alterations have an impact on nutrient handling …

Secreted microRNAs (miRNAs) are novel endocrine factors that play essential pathological
and physiological roles. Here, we report that pancreatic β cell‐released exosomal miR‐29 …

Efficient entry into S phase of the cell cycle is necessary for embryonic development and
tissue homoeostasis. However, unscheduled S phase entry triggers DNA damage and …

The gut microbiota has been evolving with its host along the time creating a symbiotic
relationship. In this study, we assess the role of the host genome in the modulation of the …

Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 (NUCKS1) has been
reported to play an oncogenic role in several cancers. However, the biological functions and …

NUCKS1 (nuclear casein kinase and cyclin-dependent kinase substrate 1) is a 27 kD
chromosomal, vertebrate-specific protein, for which limited functional data exist. Here, we …

The effects of nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 (NUCKS1)
on tumor cells and the relevant mechanisms are less well defined. This study aimed to …

Background: MicroRNA-214 (miR-214) has been shown to act as a tumour suppressor in
human cervical and colorectal cancer cells. The aim of this study was to experimentally …

Background Sarcopenia, characterized by progressive muscle mass and function loss,
particularly affects the elderly, and leads to severe consequences such as falls and mortality …