Unlocking the Therapeutic Potential of Medicinal Plants for Alzheimer's Disease: Preclinical to Clinical Trial Insights

K Nagori, KT Nakhate, K Yadav, Ajazuddin… - Future …, 2023 - mdpi.com
Alzheimer's disease (AD) is a progressive, multifactorial, and unremitting neurodegenerative
disease characterized by memory loss, personality changes, and cognitive impairment. It …

Exploring Curcumin-Loaded Lipid-Based Nanomedicine as Efficient Targeted Therapy for Alzheimer's Diseases

BF Far, M Safaei, A Pourmolaei… - ACS Applied Bio …, 2024 - ACS Publications
Alzheimer's disease (AD) is a neurological condition currently with 47 million people
suffering from it globally. AD might have many reasons such as genetic issues …

Macrophage Membrane‐Modified MoS2 Quantum Dots as a Nanodrug for Combined Multi‐Targeting of Alzheimer's Disease

X Qi, L Li, P Ye, M Xie - Advanced Healthcare Materials, 2024 - Wiley Online Library
The complex pathological mechanism of Alzheimer's disease (AD) limits the efficacy of
simple drug therapy, and drugs are difficult to penetrate the blood‐brain barrier (BBB) …

Nanomedicines for Alzheimer's disease: Therapies based on pathological mechanisms

G Cheng, A Xie, Z Yan, X Zhu, Y Song, T Chen - Brain‐X, 2023 - Wiley Online Library
Alzheimer's disease (AD) is the most common neurodegenerative disorder worldwide.
Because of the complex pathogenesis of AD and the unique location of AD lesions, effective …

[HTML][HTML] Secondary Bioactive Metabolites from Foods of Plant Origin as Theravention Agents against Neurodegenerative Disorders

TM Gomes, P Sousa, C Campos, R Perestrelo… - Foods, 2024 - mdpi.com
Neurodegenerative disorders (NDDs) such as Alzheimer's (AD) and Parkinson's (PD) are on
the rise, robbing people of their memories and independence. While risk factors such as age …

Regulation of neuroinflammation in Alzheimer's disease via nanoparticle-loaded phytocompounds with anti-inflammatory and autophagy-inducing properties

V Nayak, S Patra, S Rout, AB Jena, R Sharma… - Phytomedicine, 2024 - Elsevier
Background Alzheimer's disease (AD) is characterized by neuroinflammation linked to
amyloid β (Aβ) aggregation and phosphorylated tau (τ) protein in neurofibrillary tangles …

[HTML][HTML] Ameliorative effects of pine nut peptide-zinc chelate (Korean pine) on a mouse model of Alzheimer's disease

Z Zhang, J Sun, Y Li, K Yang, G Wei, S Zhang - Experimental Gerontology, 2023 - Elsevier
In this study, 50 SD adult male mice were used to create an Alzheimer's disease model. The
mice's learning and memory abilities were evaluated using an eight-arm radial maze …

Recent progresses in natural based therapeutic materials for Alzheimer's disease

T Zivari-Ghader, F Valioglu, A Eftekhari, N Aliyeva… - Heliyon, 2024 - cell.com
Alzheimer's disease is a neurological disorder that causes increased memory loss, mood
swings, behavioral disorders, and disruptions in daily activities. Polymer scaffolds for the …

Enhancing Targeted Therapy in Hepatocellular Carcinoma through a pH-Responsive Delivery System: Folic Acid-Modified Polydopamine-Paclitaxel-Loaded Poly (3 …

M Wu, Q Wang, Y Peng, X Liang, X Lv… - Molecular …, 2023 - ACS Publications
Currently, there is an inherent contradiction between the multifunctionality and excellent
biocompatibility of anticancer drug nanocarriers, which limits their application. Therefore, to …

Novel Strategy for Alzheimer's Disease Treatment through Oral Vaccine Therapy with Amyloid Beta

Y Matsuzaka, R Yashiro - Biologics, 2023 - mdpi.com
Alzheimer's disease (AD) is a neuropathology characterized by progressive cognitive
impairment and dementia. The disease is attributed to senile plaques, which are aggregates …