Background The production of peroxide and superoxide is an inevitable consequence of
aerobic metabolism, and while these particular'reactive oxygen species'(ROSs) can exhibit a …

Pentacoordinate respiratory hemoproteins such as hemoglobin and myoglobin have
evolved to supply cells with oxygen. However, these respiratory heme proteins are also …

Several novel antioxidant-iron chelators bearing 8-hydroxyoxyquinoline moiety were
synthesized, and various properties related to their iron chelation, and neuroprotective …

Recent research has shown that myoglobin and hemoglobin play important roles in the
pathology of certain disease states, such as renal dysfunction following rhabdomyolysis and …

Accumulating evidence suggests that there are important contributions to coronavirus
disease (COVID-19) from redox imbalance and improperly coordinated iron, which cause …

Alzheimer's disease (AD) presents a complex pathology involving amyloidogenic
proteolysis, neuroinflammation, mitochondrial dysfunction, and cholinergic deficits. Oxidative …

Iron chelators such as desferrioxamine have been shown to ameliorate oxidative damage in
vivo. The mechanism of this therapeutic action under non-iron-overload conditions is …

Background: The alkaloid 8-hydroxyquinoline (8HQ) is well-known for various biological
activities, including antioxidant effects and especially for the formation of coordination …

Oxidative stress is associated with a number of degenerative disease states, such as cancer
and AIDS. Fundamental to oxidative stress is the generation of superoxide, peroxide and …

Selected metal ions having paramagnetic property were found to exert inhibition effects on
aquatic photodegradation of organophosphorus pesticides sensitized by humic acids …