Mechanistic landscape of membrane-permeabilizing peptides
Membrane permeabilizing peptides (MPPs) are as ubiquitous as the lipid bilayer
membranes they act upon. Produced by all forms of life, most membrane permeabilizing …
membranes they act upon. Produced by all forms of life, most membrane permeabilizing …
Membrane active peptides and their biophysical characterization
In the last 20 years, an increasing number of studies have been reported on membrane
active peptides. These peptides exert their biological activity by interacting with the cell …
active peptides. These peptides exert their biological activity by interacting with the cell …
Fundamentals on the molecular mechanism of action of antimicrobial peptides
JAF Corrêa, AG Evangelista, T de Melo Nazareth… - Materialia, 2019 - Elsevier
Antimicrobial peptides (AMPs) are produced by several organisms as their first line of
defense. Constituted by amino acids, they may present different mechanisms of action. The …
defense. Constituted by amino acids, they may present different mechanisms of action. The …
Antimicrobial peptide magainin 2-induced rupture of single giant unilamellar vesicles comprising E. coli polar lipids
Most antimicrobial peptides (AMPs) damage the cell membrane of bacterial cells and induce
rapid leakage of the internal cell contents, which is a main cause of their bactericidal activity …
rapid leakage of the internal cell contents, which is a main cause of their bactericidal activity …
Elementary processes for the entry of cell-penetrating peptides into lipid bilayer vesicles and bacterial cells
Cell-penetrating peptides (CPPs) can translocate across the plasma membrane of living
eukaryotic cells and enter the cytosol without significantly affecting cell viability …
eukaryotic cells and enter the cytosol without significantly affecting cell viability …
Role of membrane potential on entry of cell-penetrating peptide transportan 10 into single vesicles
Cell-penetrating peptides (CPPs) can translocate across plasma membranes to enter the
cytosol of eukaryotic cells without decreasing cell viability. We revealed the mechanism …
cytosol of eukaryotic cells without decreasing cell viability. We revealed the mechanism …
The role of membrane tension in the action of antimicrobial peptides and cell-penetrating peptides in biomembranes
For antimicrobial peptides (AMPs) with antimicrobial and bactericidal activities and cell-
penetrating peptides (CPPs) with activity to permeate through plasma membrane, their …
penetrating peptides (CPPs) with activity to permeate through plasma membrane, their …
Action of antimicrobial peptides and cell-penetrating peptides on membrane potential revealed by the single GUV method
Membrane potential plays various key roles in live bacterial and eukaryotic cells. So far, the
effects of membrane potential on action of antimicrobial peptides (AMPs) and cell …
effects of membrane potential on action of antimicrobial peptides (AMPs) and cell …
An escape from ESKAPE pathogens: A comprehensive review on current and emerging therapeutics against antibiotic resistance
The rise of antimicrobial resistance has positioned ESKAPE pathogens as a serious global
health threat, primarily due to the limitations and frequent failures of current treatment …
health threat, primarily due to the limitations and frequent failures of current treatment …
Synergistic bactericide and antibiotic effects of dimeric, tetrameric, or palindromic peptides containing the RWQWR motif against Gram-positive and Gram-negative …
Y Vargas-Casanova, AV Rodríguez-Mayor… - RSC …, 2019 - pubs.rsc.org
Dimeric and tetrameric peptides derived from LfcinB (20–25): RRWQWR, LfcinB (20–30):
RRWQWRMKKLG, LfcinB (17–31): FKARRWQWRMKKLGA, or the palindromic sequence …
RRWQWRMKKLG, LfcinB (17–31): FKARRWQWRMKKLGA, or the palindromic sequence …