Effective clinical methods for large bone defects are not yet available on account of the
complex intrinsic structure and mechanical characteristics of natural bone tissue. It remains …

Healing large bone defects remains challenging in orthopedic surgery and is often
associated with poor outcomes and complications. A major issue with bioengineered …

Bamboo is a swiftly renewable natural material. A thorough exploration of its functional
hierarchical structure is helpful to improve its utilization efficiency. Previous studies have …

Benefiting from the development of high-brilliance synchrotron radiation sources,
microbeam X-ray scattering has become a well established scattering-based imaging …

The bone-cartilage unit (BCU) is a universal feature in diarthrodial joints, which is
mechanically-graded and subjected to shear and compressive strains. Changes in the BCU …

The complicated internal mechanical and structural qualities of normal bone tissue still
prevent the development of effective therapeutic procedures for major bone lesions. It is still …

Background Accumulated evidence has suggested that hydrogen sulfide (H 2 S) has a role
in bone formation and bone tissue regeneration. However, it is unknown whether the H 2 S …

Introduction Osteoporosis-induced changes in bone structure and composition significantly
reduce bone strength, particularly in the human proximal femur. This study examines how …

In humans, the growth pattern of the acellular extrinsic fibre cementum (AEFC) has been
useful to estimate the age-at-death. However, the structural organization behind such a …

Understanding the properties of bone is of both fundamental and clinical relevance. The
basis of bone's quality and mechanical resilience lies in its nanoscale building blocks (ie …