Life of RISC: Formation, action, and degradation of RNA-induced silencing complex

H Iwakawa, Y Tomari - Molecular cell, 2022 - cell.com
Small RNAs regulate a wide variety of biological processes by repressing the expression of
target genes at the transcriptional and post-transcriptional levels. To achieve these …

RNA-directed DNA methylation: an epigenetic pathway of increasing complexity

MA Matzke, RA Mosher - Nature Reviews Genetics, 2014 - nature.com
RNA-directed DNA methylation (RdDM) is the major small RNA-mediated epigenetic
pathway in plants. RdDM requires a specialized transcriptional machinery that comprises …

RNA-directed DNA methylation

RM Erdmann, CL Picard - PLoS genetics, 2020 - journals.plos.org
RNA-directed DNA methylation (RdDM) is a biological process in which non-coding RNA
molecules direct the addition of DNA methylation to specific DNA sequences. The RdDM …

Geminiviruses: masters at redirecting and reprogramming plant processes

L Hanley-Bowdoin, ER Bejarano… - Nature Reviews …, 2013 - nature.com
The family Geminiviridae is one of the largest and most important families of plant viruses.
The small, single-stranded DNA genomes of geminiviruses encode 5–7 proteins that …

Genomic impact of stress-induced transposable element mobility in Arabidopsis

D Roquis, M Robertson, L Yu, M Thieme… - Nucleic acids …, 2021 - academic.oup.com
Transposable elements (TEs) have long been known to be major contributors to plant
evolution, adaptation and crop domestication. Stress-induced TE mobilization is of particular …

Non-canonical RNA-directed DNA methylation

D Cuerda-Gil, RK Slotkin - Nature plants, 2016 - nature.com
Small RNA-directed DNA methylation (RdDM) has been extensively studied in plants,
resulting in a deep understanding of a major 'canonical RdDM'mechanism. However, current …

RNA interference mechanisms and applications in plant pathology

C Rosa, YW Kuo, H Wuriyanghan… - Annual review of …, 2018 - annualreviews.org
The origin of RNA interference (RNAi), the cell sentinel system widely shared among
eukaryotes that recognizes RNAs and specifically degrades or prevents their translation in …

Small RNAs in plants: recent development and application for crop improvement

A Kamthan, A Chaudhuri, M Kamthan… - Frontiers in plant …, 2015 - frontiersin.org
The phenomenon of RNA interference (RNAi) which involves sequence-specific gene
regulation by small non-coding RNAs, ie, small interfering RNA (siRNA) and microRNA …

Mapping the epigenetic basis of complex traits

S Cortijo, R Wardenaar, M Colomé-Tatché, A Gilly… - Science, 2014 - science.org
Quantifying the impact of heritable epigenetic variation on complex traits is an emerging
challenge in population genetics. Here, we analyze a population of isogenic Arabidopsis …

The role of viruses in identifying and analyzing RNA silencing

DC Baulcombe - Annual Review of Virology, 2022 - annualreviews.org
Adaptive antiviral immunity in plants is an RNA-based mechanism in which small RNAs
derived from both strands of the viral RNA are guides for an Argonaute (AGO) nuclease. The …