Apoptotic bodies: bioactive treasure left behind by the dying cells with robust diagnostic and therapeutic application potentials
L Yu, G Zhu, Z Zhang, Y Yu, L Zeng, Z Xu… - Journal of …, 2023 - Springer
Apoptosis, a form of programmed cell death, is essential for growth and tissue homeostasis.
Apoptotic bodies (ApoBDs) are a form of extracellular vesicles (EVs) released by dying cells …
Apoptotic bodies (ApoBDs) are a form of extracellular vesicles (EVs) released by dying cells …
Molecular mechanisms and clinical application of multipotent stem cells for spinal cord injury
M Szymoniuk, J Litak, L Sakwa, A Dryla, W Zezuliński… - Cells, 2022 - mdpi.com
Spinal Cord Injury (SCI) is a common neurological disorder with devastating psychical and
psychosocial sequelae. The majority of patients after SCI suffer from permanent disability …
psychosocial sequelae. The majority of patients after SCI suffer from permanent disability …
Bone mesenchymal stem cell-derived exosomal microRNA-7-5p inhibits progression of acute myeloid leukemia by targeting OSBPL11
D Jiang, X Wu, X Sun, W Tan, X Dai, Y Xie, A Du… - Journal of …, 2022 - Springer
Background Acute myeloid leukemia (AML) is a malignant clonal disease of hematopoietic
stem-and progenitor-cell origin. AML features massive proliferation of abnormal blasts and …
stem-and progenitor-cell origin. AML features massive proliferation of abnormal blasts and …
The bone mesenchymal stem cell-derived exosomal miR-146a-5p promotes diabetic wound healing in mice via macrophage M1/M2 polarization
X Zhou, C Ye, L Jiang, X Zhu, F Zhou, M Xia… - Molecular and Cellular …, 2024 - Elsevier
A diabetic wound is a refractory disease that afflicts patients globally. MicroRNA-146a-5p
(miR-146a-5p) is reported to represent a potential therapeutic target for diabetic wounds …
(miR-146a-5p) is reported to represent a potential therapeutic target for diabetic wounds …
Advances of mesenchymal stem cells and their derived extracellular vesicles as a promising therapy for acute respiratory distress syndrome: from bench to clinic
X Zhuang, Y Jiang, X Yang, L Fu, L Luo… - Frontiers in …, 2023 - frontiersin.org
Acute respiratory distress syndrome (ARDS) is an acute inflammatory lung injury
characterized by diffuse alveolar damage. The period prevalence of ARDS was 10.4% of …
characterized by diffuse alveolar damage. The period prevalence of ARDS was 10.4% of …
Mesenchymal stem cells as a gene delivery tool: Promise, problems, and prospects
The cell-based approach in gene therapy arises as a promising strategy to provide safe,
targeted, and efficient gene delivery. Owing to their unique features, as homing and tumor …
targeted, and efficient gene delivery. Owing to their unique features, as homing and tumor …
Cell-based therapy for the treatment of glioblastoma: an update from preclinical to clinical studies
Glioblastoma (GB), an aggressive primary tumor of the central nervous system, represents
about 60% of all adult primary brain tumors. It is notorious for its extremely low (~ 5%) 5-year …
about 60% of all adult primary brain tumors. It is notorious for its extremely low (~ 5%) 5-year …
Cholesterol-linoleic acid liposomes induced extracellular vesicles secretion from immortalized adipose-derived mesenchymal stem cells for in vitro cell migration
Extracellular vesicles (EVs) are small vesicles that are naturally released by cells and play a
crucial role in cell-to-cell communication, tissue repair and regeneration. As naturally …
crucial role in cell-to-cell communication, tissue repair and regeneration. As naturally …
Mesenchymal stromal cell-derived extracellular vesicles as biological carriers for drug delivery in cancer therapy
MC Sanmartin, FR Borzone, MB Giorello… - … in Bioengineering and …, 2022 - frontiersin.org
Cancer is the second leading cause of death worldwide, with 10.0 million cancer deaths in
2020. Despite advances in targeted therapies, some pharmacological drawbacks …
2020. Despite advances in targeted therapies, some pharmacological drawbacks …
Stability of polymeric cationic niosomes and their plasmid DNA-based complexes as gene delivery carriers
This study aims to explore the stability of lipo-polymeric niosomes/niosome-based pCMS-
EGFP complexes under different storage temperatures (25° C, 4° C, and− 20° C). To date …
EGFP complexes under different storage temperatures (25° C, 4° C, and− 20° C). To date …