Significance: Measurement and imaging of hemoglobin oxygenation are used extensively in
the detection and diagnosis of disease; however, the applied instruments vary widely in their …

Purpose To assess initial breast tumor hemoglobin (Hb) content before the initiation of
neoadjuvant chemotherapy, monitor the Hb changes at the end of each treatment cycle, and …

Wide-field optical imaging techniques constitute powerful tools to investigate mesoscale
neuronal activity. The sampled data constitutes a sequence of image frames in which one …

Sustained angiogenesis is essential for the development of solid tumors and metastatic
disease. Disruption of signaling pathways that govern tumor vascularity provide a potential …

Significance: We demonstrate the potential of probing the sO2 change under blood flow in
vivo using photoacoustic (PA) imaging and sheds light on the complex relationship between …

Optoacoustic imaging (OAI) can detect haemoglobin and assess its oxygenation. However,
the lack of a haemoglobin signal need not indicate a lack of perfusion. This study uses a …

Significance There is a need for a cost-effective, quantitative imaging tool that can be
deployed endoscopically to better detect early stage gastrointestinal cancers. Spatial …

Featured Application This work describes a new hybrid diffuse optical imaging (DOI) method
that extracts broadband optical properties of deep tumor-like inhomogeneities with a simple …

Objective. MamoRef is an mammography device that uses near-infrared light, designed to
provide clinically relevant information for the screening of diseases of the breast. Using low …

Introduction Bilateral reduction mammoplasty (BRM) aims to alleviate macromastia-related
symptoms in women. This procedure involves a T-Junction suture at the medial …