Cellular agriculture is an emerging scientific discipline that leverages the existing principles
behind stem cell biology, tissue engineering, and animal sciences to create agricultural …

The survival of engineered tissue constructs during the initial phase after their implantation
depends on the rapid development of an adequate vascularization. This, in turn, is a major …

Volumetric muscle loss (VML) is associated with loss of skeletal muscle function, and current
treatments show limited efficacy. Here we show that bioconstructs suffused with genetically …

This review discusses historical milestones, recent developments and challenges in the
area of 3D culture models with cardiovascular cell types. Expectations in this area have …

The development of laboratory-grown tissues, referred to as organoids, bio-artificial tissue or
tissue-engineered constructs, is clearly expanding. We describe for the first time how …

Reconfiguring the structure and selectivity of existing chemotherapeutics represents an
opportunity for developing novel tumor‐selective drugs. Here, as a proof‐of‐concept, the …

Meat is the main protein source of the human diet in many cultures. Because of the
increasing population growth and welfare, the conventional meat industry cannot follow …

The control of the in vivo vascularization of engineered tissue substitutes is essential in
order to obtain either a rapid induction or a complete inhibition of the process (eg in muscles …

Hydrostatic pressure (HP) and osmotic stress (OS) play an important role in various
biological processes, such as cell proliferation and differentiation. In contrast to canonical …

A common shortcoming of current tissue engineered constructs is the lack of a functional
vasculature, limiting their size and functionality. Prevascularization is a possible strategy to …