Genetic associations between voltage-gated calcium channels and psychiatric disorders

A Andrade, A Brennecke, S Mallat, J Brown… - International journal of …, 2019 - mdpi.com
Psychiatric disorders are mental, behavioral or emotional disorders. These conditions are
prevalent, one in four adults suffer from any type of psychiatric disorders world-wide. It has …

[HTML][HTML] From gene to behavior: L-type calcium channel mechanisms underlying neuropsychiatric symptoms

ZD Kabir, A Martínez-Rivera, AM Rajadhyaksha - Neurotherapeutics, 2017 - Elsevier
The L-type calcium channels (LTCCs) Ca v 1.2 and Ca v 1.3, encoded by the CACNA1C
and CACNA1D genes, respectively, are important regulators of calcium influx into cells and …

Evaluation of voltage-dependent calcium channel γ gene families identified several novel potential susceptible genes to schizophrenia

F Guan, T Zhang, X Liu, W Han, H Lin, L Li, G Chen… - Scientific reports, 2016 - nature.com
Voltage-gated L-type calcium channels (VLCC) are distributed widely throughout the brain.
Among the genes involved in schizophrenia (SCZ), genes encoding VLCC subunits have …

Common variants in SLC1A2 and schizophrenia: Association and cognitive function in patients with schizophrenia and healthy individuals

B Zhang, F Guan, G Chen, H Lin, T Zhang, J Feng… - Schizophrenia …, 2015 - Elsevier
SLC1A2 is reported to be responsible for the majority of glutamate uptake, which has a
crucial role in neural development and synaptic plasticity, and a disturbance in …

Genetic polymorphisms of GZMB and vitiligo: A genetic association study based on Chinese Han population

M Xu, Y Liu, Y Liu, X Li, G Chen, W Dong, S Xiao - Scientific reports, 2018 - nature.com
Vitiligo is a skin disease that affects 1% of the population worldwide. Both environmental
and genetic factors contribute to the risk of vitiligo. GZMB encodes the enzyme Granzyme B …

CACNA1D-Related Channelopathies: From Hypertension to Autism

NJ Ortner - … -gated Ca2+ Channels: Pharmacology, Modulation and …, 2023 - Springer
Tightly controlled Ca2+ influx through voltage-gated Ca2+ channels (Cavs) is indispensable
for proper physiological function. Thus, it is not surprising that Cav loss and/or gain of …

Relationship of common variants in VEGFA gene with osteonecrosis of the femoral head: A Han Chinese population based association study

W Ma, K Xin, K Chen, H Tang, H Chen, L Zhi, H Liu - Scientific reports, 2018 - nature.com
The pathology of non-traumatic osteonecrosis of the femoral head (ONFH) is complex.
Several studies have linked some polymorphisms of vascular endothelial growth factors A …

Genetic susceptibility of postmenopausal osteoporosis on sulfide quinone reductase-like gene

X Cai, X Yi, Y Zhang, D Zhang, L Zhi, H Liu - Osteoporosis International, 2018 - Springer
Postmenopausal osteoporosis is a major health problem with important genetic factors in
postmenopausal women. We explored the relationship between SQRDL and osteoporosis …

Zebrafish Larvae Carrying a Splice Variant Mutation in cacna1d: A New Model for Schizophrenia-Like Behaviours?

NS Banono, K Gawel, L De Witte, CV Esguerra - Molecular Neurobiology, 2021 - Springer
Persons with certain single nucleotide polymorphisms (SNPs) in the CACNA1D gene
(encoding voltage-gated calcium channel subunit alpha 1-D) have increased risk of …

Relationship of common variants in MPP7, TIMP2 and CASP8 genes with the risk of chronic achilles tendinopathy

X Kang, B Tian, L Zhang, Z Ge, Y Zhao, Y Zhang - Scientific Reports, 2019 - nature.com
Previous etiologic studies have indicated that both environmental and genetic factors play
important roles in the occurrence and development of chronic Achilles tendinopathy (AT). A …