Highlights•miRNAs and RISC are located near synapses.•miRNAs regulate local protein
synthesis in dendrites and axons.•miRNAs play important roles in synapse development and …

Pathogenic processes underlying Alzheimer's disease (AD) affect synaptic function from
initial asymptomatic stages, long time before the onset of cognitive decline and …

Neuroinflammation causes neuronal injury in multiple sclerosis (MS) and other neurological
diseases. MicroRNAs (miRNAs) are important modulators of neuronal stress responses, but …

DNA that controls gene expression (eg enhancers, promoters) has seemed almost never to
be conserved between distantly related animals, like vertebrates and arthropods. This is …

Post-traumatic stress disorder (PTSD) is a neuropsychiatric disorder occurring in susceptible
individuals following a traumatic event. Understanding the mechanisms subserving trauma …

Drug addiction is characterized by uncontrolled drug consumption and high rates of relapse
to drug taking during periods of attempted abstinence. Addiction is now largely considered a …

Learning and memory formation rely on the precise spatiotemporal regulation of gene
expression, such as microRNA (miRNA)-associated silencing, to fine-tune gene expression …

MicroRNAs (miRNAs) are dysregulated in many types of malignancies, including human
hepatocellular carcinoma (HCC). MiR-107 has been implicated in several types of cancer …

Given the high prevalence of stress-related mental disorders, their impact on person, family,
and society and the paucity of treatment options for most of these disorders, there is currently …

MicroRNAs are a class of non-coding RNAs with a growing relevance in the regulation of
gene expression related to brain function and plasticity. They have the potential to …