Coronary heart disease (CHD) is a type of cardiovascular disease (CVD) that affects the
coronary arteries, which provide oxygenated blood to the heart. It is a major cause of …

Epigenetic modifications play a fundamental role in the progression of coronary artery
disease (CAD). This panoramic review aims to provide an overview of the current …

Genetic and epigenetic modifications of genes involved in the key regulatory pathways play
a significant role in the pathophysiology and progression of multifactorial diseases. The …

Cardiovascular diseases are the foremost contributor to global mortality, presenting a
complex etiology and an expanding array of risk factors. Coronary artery disease …

O-linked glycosylation, the greatest form of post-translational modifications, plays a key role
in regulating the majority of physiological processes. It is, therefore, not surprising that …

Over the last few years, the development of so-called omics technologies has greatly
contributed to the discovery of new biomarkers and targets, embracing various fields from …

Despite extensive clinical research and management protocols applied in the field of
coronary artery diseases (CAD), it still holds the number 1 position in mortality worldwide …

The APOA1/C3/A4/A5 cluster is an essential component in regulating lipoprotein
metabolism and maintaining plasma lipid homeostasis. A genome-wide association analysis …

Radiotherapy in cancer treatment involves the use of ionizing radiation for cancer cell killing.
Although radiotherapy has shown significant improvements on cancer recurrence and …

Aim: Methylation of LDLR, PCSK9 and LDLRAP1 CpG sites was assessed in patients with
familial hypercholesterolemia (FH). Methods: DNA methylation of was analyzed by …