Free radicals are ubiquitous in our body and are generated by normal physiological
processes, including aerobic metabolism and inflammatory responses, to eliminate invading …

Significance: The mitochondrial antioxidant manganese superoxide dismutase (MnSOD) is
encoded by genomic DNA and its dismutase function is fully activated in the mitochondria to …

Uric acid is considered a major antioxidant in human blood that may protect against aging
and oxidative stress. Despite its proposed protective properties, elevated levels of uric acid …

During the past decade a plethora of studies have unravelled the multiple roles of nitric
oxide (NO) in airway physiology and pathophysiology. In the respiratory tract, NO is …

Saliva is an interesting alternative diagnostic body fluid with several specific advantages
over blood. These include non-invasive and easy collection and related possibility to do …

Nitrite is one of the players in the broad nitrogen biogeochemical cycle. This nitrogen oxo-
anion is involved in key pathways crucial to life on Earth and to the planetary “recycling” of …

IDO1 (indoleamine 2, 3-dioxygenase 1) is a member of a unique class of mammalian haem
dioxygenases that catalyse the oxidative catabolism of the least-abundant essential amino …

Nitrate is a natural constituent of the human diet and an approved food additive. It can be
partially converted to nitrogen monoxide, which induces vasodilation and thereby decreases …

The use of nitric oxide (NO) is emerging as a promising, novel approach for the treatment of
antibiotic resistant bacteria and biofilm infections. Depending on the concentration, NO can …

Protein S‐glutathiolation, the reversible covalent addition of glutathione to cysteine residues
on target proteins, is emerging as a candidate mechanism by which both changes in the …