The current treatment strategies in advanced malignancies remain limited. Notably,
immunotherapies have raised hope for a successful control of these advanced diseases, but …

The success of cancer immunotherapy relies on the knowledge of the tumor
microenvironment and the immune evasion mechanisms in which the tumor, stroma, and …

Macrophages infiltrating tumour tissues or residing in the microenvironment of solid tumours
are known as tumour-associated macrophages (TAMs). These specialized immune cells …

Tumor microenvironment (TME) is composed of tumor cells and surrounding non-tumor
stromal cells, mainly including tumor associated macrophages (TAMs), endothelial cells …

Anaplastic thyroid carcinoma (ATC) is a rare malignancy, accounting for 1–2% of all thyroid
cancers. Although rare, ATC accounts for the majority of deaths from thyroid carcinoma. ATC …

Liver cancer is the second leading cause of cancer mortality worldwide, causing more than
700,000 deaths annually. Because of the wide landscape of genomic alterations and limited …

The macrophage is a key cell in the pro-and anti-inflammatory response including that of the
inflammatory microenvironment of malignant tumors. Much current drug development in …

The progression and metastatic capacity of solid tumors are strongly influenced by immune
cells in the tumor microenvironment. In non–small cell lung cancer (NSCLC), accumulation …

Tumorigenesis is not only determined by the intrinsic properties of cancer cells but also by
their interactions with components of the tumor microenvironment (TME). Tumor‐associated …

A hallmark of cancer is the ability of tumor cells to avoid immune destruction. Activated
immune cells in tumor microenvironment (TME) secrete proinflammatory cytokines and …