The relationship between gut microbiota and COVID-19 progression: new insights into immunopathogenesis and treatment

M Wang, Y Zhang, C Li, W Chang, L Zhang - Frontiers in Immunology, 2023 - frontiersin.org
The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has posed a global health crisis. Increasing …

ACE2 in chronic disease and COVID-19: gene regulation and post-translational modification

CW Wang, HC Chuang, TH Tan - Journal of Biomedical Science, 2023 - Springer
Abstract Angiotensin-converting enzyme 2 (ACE2), a counter regulator of the renin-
angiotensin system, provides protection against several chronic diseases. Besides chronic …

USP2 inhibition prevents infection with ACE2-dependent coronaviruses in vitro and is protective against SARS-CoV-2 in mice

F Dang, L Bai, J Dong, X Hu, J Wang… - Science Translational …, 2023 - science.org
Targeting angiotensin-converting enzyme 2 (ACE2) represents a promising and effective
approach to combat not only the COVID-19 pandemic but also potential future pandemics …

SARS-CoV-2 infection and its effects on the endocrine system

C Steenblock, N Toepfner, F Beuschlein… - Best Practice & …, 2023 - Elsevier
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing corona virus
disease 2019 (COVID-19) can infect multiple tissues, including endocrine organs, such as …

SARS-CoV-2 RBD and its variants can induce platelet activation and clearance: Implications for antibody therapy and vaccinations against COVID-19

X Ma, J Liang, G Zhu, P Bhoria, AA Shoara… - Research, 2023 - spj.science.org
The COVID-19 pandemic caused by SARS-CoV-2 virus is an ongoing global health burden.
Severe cases of COVID-19 and the rare cases of COVID-19 vaccine-induced-thrombotic …

Type 1 diabetes: A new vision of the disease based on endotypes

CS Weston, BO Boehm, P Pozzilli - … /Metabolism Research and …, 2024 - Wiley Online Library
Diagnosis and management of type 1 diabetes (T1D) have remained largely unchanged for
the last several years. The management of the disease remains primarily focused on its …

[HTML][HTML] Characterization of SARS-CoV-2 replication in human H1299/ACE2 cells: A versatile and practical infection model for antiviral research and beyond

C Salgado-Benvindo, A Tas, JC Zevenhoven-Dobbe… - Antiviral Research, 2024 - Elsevier
A range of cell culture infection models have been used to study SARS-CoV-2 and perform
antiviral drug research. Commonly used African green monkey Vero, human lung-derived …

The role of furin in the pathogenesis of COVID-19-associated neurological disorders

G Ayyubova, SG Gychka, SI Nikolaienko… - Life, 2024 - mdpi.com
Neurological disorders have been reported in a large number of coronavirus disease 2019
(COVID-19) patients, suggesting that this disease may have long-term adverse neurological …

Luminescent reporter cells enable the identification of broad‐spectrum antivirals against emerging viruses

K Löw, R Möller, C Stegmann, M Becker… - Journal of medical …, 2023 - Wiley Online Library
The emerging viruses SARS‐CoV‐2 and arenaviruses cause severe respiratory and
hemorrhagic diseases, respectively. The production of infectious particles of both viruses …

The basis of complications in the context of SARS-CoV-2 infection: pathological activation of ADAM17

S Jiang, H Yang, Z Sun, Y Zhang, Y Li, J Li - Biochemical and Biophysical …, 2023 - Elsevier
The virulence of SARS-CoV-2 decreases with increasing infectivity, the primary approaches
for antiviral treatments will be preventing or minimizing the complications resulting from virus …