Mammalian models including non‐human primates, pigs and rodents have been used
extensively to study the mechanisms of cardiovascular disease. However, there is an …

Excessive trabeculation, often referred to as “noncompacted” myocardium, has been
described at all ages, from the fetus to the adult. Current evidence for myocardial …

The evidence is increasing that left ventricular noncompaction cardiomyopathy as it is
currently defined does not represent a failure of compaction of pre-existing trabecular …

Heart development is topographically complex and requires visualization to understand its
progression. No comprehensive 3-dimensional primer of human cardiac development is …

Hypertrabeculation and noncompaction are congenital or acquired abnormalities of
myocardial anatomy characterized by prominent trabeculations, intertrabecular recesses …

The remodeling of the compact wall by incorporation of trabecular myocardium, referred to
as compaction, receives much attention because it is thought that its failure causes left …

Background Ventricular noncompaction is characterized by excessive trabeculations and is
associated with heart failure. The lesion is hypothesized to result from failed compaction and …

The complete division of the atrial cavity by a septum, resulting in a left and right atrium, is
found in many amphibians and all amniotes (reptiles, birds, and mammals). Surprisingly, it is …

The electrocardiogram (ECG) reveals that heart chamber activation and repolarization are
much faster in mammals and birds compared to ectothermic vertebrates of similar size …

Cardiomyocyte proliferation is crucial for cardiac growth, patterning and regeneration;
however, few studies have investigated the behavior of dividing cardiomyocytes in vivo …