Nanoparticle processing: Understanding and controlling aggregation

S Shrestha, B Wang, P Dutta - Advances in colloid and interface science, 2020 - Elsevier
Nanoparticles (NPs) are commonly defined as particles with size< 100 nm and are currently
of considerable technological and academic interest, since they are often the starting …

Freeze-drying of nanoparticles: How to overcome colloidal instability by formulation and process optimization

E Trenkenschuh, W Friess - European journal of pharmaceutics and …, 2021 - Elsevier
Lyophilization of nanoparticle (NP) suspensions is a promising technology to improve
stability, especially during long-term storage, and offers new routes of administration in solid …

Nonporous silica nanoparticles for nanomedicine application

L Tang, J Cheng - Nano today, 2013 - Elsevier
Nanomedicine, the use of nanotechnology for biomedical applications, has potential to
change the landscape of the diagnosis and therapy of many diseases. In the past several …

Nonviral vectors for gene delivery

MA Mintzer, EE Simanek - Chemical reviews, 2009 - ACS Publications
Gene therapy has gained significant attention over the past two decades as a potential
method for treating genetic disorders such as severe combined immunodeficiency, 1 cystic …

Freeze-drying of nanoparticles: formulation, process and storage considerations

W Abdelwahed, G Degobert, S Stainmesse… - Advanced drug delivery …, 2006 - Elsevier
Freeze-drying has been considered as a good technique to improve the long-term stability of
colloidal nanoparticles. The poor stability in an aqueous medium of these systems forms a …

To protect and to preserve: novel preservation strategies for extracellular vesicles

GD Kusuma, M Barabadi, JL Tan… - Frontiers in …, 2018 - frontiersin.org
Extracellular vesicles (EVs)-based therapeutics are based on the premise that EVs shed by
stem cells exert similar therapeutic effects and these have been proposed as an alternative …

Mesoporous silica nanoparticles deliver DNA and chemicals into plants

F Torney, BG Trewyn, VSY Lin, K Wang - Nature nanotechnology, 2007 - nature.com
Surface-functionalized silica nanoparticles can deliver DNA,,,,,,, and drugs,,,,,, into animal
cells and tissues. However, their use in plants is limited by the cell wall present in plant cells …

Methods for the preparation and manufacture of polymeric nanoparticles

C Vauthier, K Bouchemal - Pharmaceutical research, 2009 - Springer
This review summarizes the different methods of preparation of polymer nanoparticles
including nanospheres and nanocapsules. The first part summarizes the basic principle of …

Facts and evidences on the lyophilization of polymeric nanoparticles for drug delivery

P Fonte, S Reis, B Sarmento - Journal of controlled release, 2016 - Elsevier
Lyophilization has been used to improve the long-term stability of polymeric nanoparticles
for drug delivery applications, avoiding their instability in suspension. However, this …

Nanostructure-mediated drug delivery

GA Hughes - Nanomedicine: nanotechnology, biology and medicine, 2005 - Elsevier
Nanotechnology is expected to have an impact on all industries including semiconductors,
manufacturing, and biotechnology. Tools that provide the capability to characterize and …