Idiopathic pulmonary fibrosis (IPF) is a progressive, lethal fibrotic lung disease that occurs
primarily in middle-aged and elderly adults. It is a major cause of morbidity and mortality …

The basic unit of chromatin, the nucleosome, is an octamer of four core histone proteins
(H2A, H2B, H3, and H4) and serves as a fundamental regulatory unit in all DNA-templated …

Although metal single‐atom (SA)‐based nanomaterials are explored as sonosensitizers for
sonodynamic therapy (SDT), they normally exhibit poor activities and need to combine with …

Fibrosis is a condition characterized by the excessive accumulation of extracellular matrix
proteins in tissues, leading to organ dysfunction and failure. Recent studies have identified …

Background: Small cell lung cancer (SCLC) is an extremely aggressive cancer type with a
patient median survival of 6-12 months. Epidermal growth factor (EGF) signaling plays an …

R-loops are trimeric nucleic acid structures that form when an RNA molecule hybridizes with
its complementary DNA strand, displacing the opposite strand. These structures regulate …

Complex molecular mechanisms define our responses to environmental stimuli. Beyond the
DNA sequence itself, epigenetic machinery orchestrates changes in gene expression …

Identification of factors that regulate chromatin condensation is important for understanding
of gene regulation. High-mobility group AT-hook (HMGA) proteins 1 and 2 are abundant …

Inflammatory bowel diseases (IBD) are chronic inflammatory disorders of the gastrointestinal
tract that encompass two main phenotypes, namely Crohn's disease and ulcerative colitis …

Background Our previous study demonstrated that Guanxin V (GXV), a traditional Chinese
herbal medicine, has a significant therapeutic effect on ventricular remodeling. However, the …