The current landscape of glioblastoma biomarkers in body fluids

S Zanganeh, E Abbasgholinejad, M Doroudian… - Cancers, 2023 - mdpi.com
Simple Summary Glioblastoma is a highly aggressive brain cancer, and early detection and
accurate diagnosis are crucial for effective treatment. Traditional diagnostic methods have …

Challenges and Promise for Glioblastoma Treatment through Extracellular Vesicle Inquiry

GL Liguori - Cells, 2024 - mdpi.com
Glioblastoma (GB) is a rare but extremely aggressive brain tumor that significantly impacts
patient outcomes, affecting both duration and quality of life. The protocol established by …

Extracellular vesicles secreted by glioma stem cells are involved in radiation resistance and glioma progression

C Ma, HPT Nguyen, JJ Jones, SS Stylli… - International Journal of …, 2022 - mdpi.com
Glioblastoma is the most aggressive brain tumour with short survival, partly due to resistance
to conventional therapy. Glioma stem cells (GSC) are likely to be involved in treatment …

Hsp70 and Calcitonin Receptor Protein in Extracellular Vesicles from Glioblastoma Multiforme: Biomarkers with Putative Roles in Carcinogenesis and Potential for …

G Alberti, CM Sánchez-López, A Marcilla… - International Journal of …, 2024 - mdpi.com
Glioblastoma multiforme (GBM) is a malignancy of bad prognosis, and advances in early
detection and treatment are needed. GBM is heterogenous, with varieties differing in …

Triphenylphosphonium-functionalized N-heterocyclic carbene platinum complexes [(NHC-TPP+) Pt] induce cell death of human glioblastoma cancer stem cells

PF de Larrinoa, J Parmentier, A Kichler… - International Journal of …, 2023 - Elsevier
A growing body of experimental and clinical evidence suggests that rare cell populations,
known as cancer stem cells (CSCs), play an important role in the development and …

Development of WRAP5 peptide complexes for targeted drug/gene co-delivery toward glioblastoma therapy

AR Neves, T Albuquerque, R Faria, AM Gonçalves… - Pharmaceutics, 2022 - mdpi.com
Despite the great progress over the past few decades in both the diagnosis and treatment of
a great variety of human cancers, glioblastoma remains the most lethal brain tumor. In recent …

Targeting the Endocannabinoid System Present in the Glioblastoma Tumour Microenvironment as a Potential Anti-Cancer Strategy

MH Dasram, P Naidoo, RB Walker… - International Journal of …, 2024 - mdpi.com
The highly aggressive and invasive glioblastoma (GBM) tumour is the most malignant lesion
among adult-type diffuse gliomas, representing the most common primary brain tumour in …

Applications of exosomes in diagnosing muscle invasive bladder cancer

JM Walker, P O'Malley, M He - Pharmaceutics, 2022 - mdpi.com
Muscle Invasive Bladder Cancer (MIBC) is a subset of bladder cancer with a significant risk
for metastases and death. It accounts for nearly 25% of bladder cancer diagnoses. A …

Particulate Matters Affecting lncRNA Dysregulation and Glioblastoma Invasiveness: In Silico Applications and Current Insights

S Mukherjee, U Kundu, D Desai, PP Pillai - Journal of Molecular …, 2022 - Springer
With a reported rise in global air pollution, more than 50% of the population remains
exposed to toxic air pollutants in the form of particulate matters (PMs). PMs, from various …

[HTML][HTML] Proteomics Studies on Extracellular Vesicles Derived from Glioblastoma: Where Do We Stand?

P Giuliani, C De Simone, G Febo, A Bellasame… - International Journal of …, 2024 - mdpi.com
Like most tumors, glioblastoma multiforme (GBM), the deadliest brain tumor in human
adulthood, releases extracellular vesicles (EVs). Their content, reflecting that of the tumor of …