Apoptosis is a form of regulated cell death (RCD) that involves proteases of the caspase
family. Pharmacological and genetic strategies that experimentally inhibit or delay apoptosis …

Mitochondrial permeability transition (mPT) is a phenomenon that abruptly causes the flux of
low molecular weight solutes (molecular weight up to 1,500) across the generally …

Cell death is a fundamental physiological process in all living organisms. Its roles extend
from embryonic development, organ maintenance, and aging to the coordination of immune …

Ferroptosis, a recently identified and iron-dependent cell death, differs from other cell death
such as apoptosis, necroptosis, pyroptosis, and autophagy-dependent cell death. This form …

The term ferroptosis coined in 2012 causes acute kidney injury (AKI). However, its pathway
mechanism in AKI is poorly understood. In this study, we conducted an RNA-sequence …

Cell death is an essential process in all living organisms and occurs through different
mechanisms. The three main types of programmed cell death are apoptosis, pyroptosis, and …

Chronic kidney disease (CKD) is a devastating condition that is reaching epidemic levels
owing to the increasing prevalence of diabetes mellitus, hypertension and obesity, as well …

Disorders of cell number that result from an imbalance between the death of parenchymal
cells and the proliferation or recruitment of maladaptive cells contributes to the pathogenesis …

Parkinson's disease (PD) is the second most common neurodegenerative disease
worldwide. Motor deficits usually associated with PD correlate with dopaminergic axonal …

Acute kidney injury (AKI) is morphologically characterized by a synchronized plasma
membrane rupture of cells in a specific section of a nephron, referred to as acute tubular …