After several decades of intensive efforts, safe injectable preparations capable of effectively
delivering O2 to tissues and removing CO2, ie, so-called blood substitutes, appear to be …

In this review we consider the effects of endogenous and pharmacological levels of nitrite
under conditions of hypoxia. In humans, the nitrite anion has long been considered as …

Cellular therapeutics show great promise for the treatment of disease, but few noninvasive
techniques exist for monitoring the cells after administration. Here we present a magnetic …

This article describes an in vivo imaging method for visualizing and quantifying a specific
cell population. Cells are labeled ex vivo with a perfluoropolyether nanoparticle tracer agent …

1.2. Background Fluorine NMR offers many attractive features, most notably detection
sensitivity approaching that of protons. 19 F has a nuclear spin I= 1/2, a gyromagnetic ratio …

The fluorine atom provides an exciting tool for diverse spectroscopic and imaging
applications using Magnetic Resonance. The organic chemistry of fluorine is widely …

The effect of the oxygen inhalation on relaxation times was evaluated in various tissues,
including the myocardium, liver, spleen, skeletal muscle, subcutaneous fat, bone marrow …

Perfluorocarbons (PFCs) are fluorinated compounds that have been used for many years in
clinics mainly as gas/oxygen carriers and for liquid ventilation. Besides this main application …

Perfluorochemicals are a class of compounds composed entirely of carbon and fluorine
atoms. They were made famous when Clark and GolIan [1] demonstrated their …

Publisher Summary This chapter discusses the measurement of changes in tumor
oxygenation. The oxygen pressure determinations could be of great clinical value and they …