[HTML][HTML] From purines to purinergic signalling: molecular functions and human diseases
Purines and their derivatives, most notably adenosine and ATP, are the key molecules
controlling intracellular energy homoeostasis and nucleotide synthesis. Besides, these …
controlling intracellular energy homoeostasis and nucleotide synthesis. Besides, these …
Interindividual differences in caffeine metabolism and factors driving caffeine consumption
A Nehlig - Pharmacological reviews, 2018 - ASPET
Most individuals adjust their caffeine intake according to the objective and subjective effects
induced by the methylxanthine. However, to reach the desired effects, the quantity of …
induced by the methylxanthine. However, to reach the desired effects, the quantity of …
[HTML][HTML] The safety of ingested caffeine: a comprehensive review
Caffeine is the most widely consumed psychoactive drug in the world. Natural sources of
caffeine include coffee, tea, and chocolate. Synthetic caffeine is also added to products to …
caffeine include coffee, tea, and chocolate. Synthetic caffeine is also added to products to …
[HTML][HTML] Date Palm Tree (Phoenix dactylifera L.): Natural Products and Therapeutic Options
RA Al-Alawi, JH Al-Mashiqri, JSM Al-Nadabi… - Frontiers in plant …, 2017 - frontiersin.org
Many plants, including some of the commonly consumed herbs and spices in our daily food,
can be safely and effectively used to prevent and/or treat some health concerns. For …
can be safely and effectively used to prevent and/or treat some health concerns. For …
How does adenosine control neuronal dysfunction and neurodegeneration?
RA Cunha - Journal of neurochemistry, 2016 - Wiley Online Library
The adenosine modulation system mostly operates through inhibitory A1 (A1R) and
facilitatory A2A receptors (A2AR) in the brain. The activity‐dependent release of adenosine …
facilitatory A2A receptors (A2AR) in the brain. The activity‐dependent release of adenosine …
[HTML][HTML] Developmental consequences of fetal exposure to drugs: what we know and what we still must learn
EJ Ross, DL Graham, KM Money… - …, 2015 - nature.com
Most drugs of abuse easily cross the placenta and can affect fetal brain development. In
utero exposures to drugs thus can have long-lasting implications for brain structure and …
utero exposures to drugs thus can have long-lasting implications for brain structure and …
Caffeine acts through neuronal adenosine A2A receptors to prevent mood and memory dysfunction triggered by chronic stress
MP Kaster, NJ Machado, HB Silva… - Proceedings of the …, 2015 - National Acad Sciences
The consumption of caffeine (an adenosine receptor antagonist) correlates inversely with
depression and memory deterioration, and adenosine A2A receptor (A2AR) antagonists …
depression and memory deterioration, and adenosine A2A receptor (A2AR) antagonists …
[HTML][HTML] Caffeine intake exerts dual genome-wide effects on hippocampal metabolism and learning-dependent transcription
I Paiva, L Cellai, C Meriaux, L Poncelet… - The Journal of …, 2022 - Am Soc Clin Investig
JCI - Caffeine intake exerts dual genome-wide effects on hippocampal metabolism and
learning-dependent transcription Go to JCI Insight About Editors Consulting Editors For authors …
learning-dependent transcription Go to JCI Insight About Editors Consulting Editors For authors …
Convergence of adenosine and GABA signaling for synapse stabilization during development
F Gomez-Castro, S Zappettini, JC Pressey, CG Silva… - Science, 2021 - science.org
INTRODUCTION During development, brain circuits go through phases of synapse
formation, stabilization, or elimination. γ-aminobutyric acid–mediated (GABAergic) synapse …
formation, stabilization, or elimination. γ-aminobutyric acid–mediated (GABAergic) synapse …
Caffeine in preterm infants: where are we in 2020?
The incidence of preterm birth is increasing, leading to a growing population with potential
long-term pulmonary complications. Apnoea of prematurity (AOP) is one of the major …
long-term pulmonary complications. Apnoea of prematurity (AOP) is one of the major …