Molecular mechanisms of polymyxin resistance: knowns and unknowns
S Baron, L Hadjadj, JM Rolain, AO Olaitan - International journal of …, 2016 - Elsevier
Colistin, also referred to as polymyxin E, is an effective antibiotic against most multidrug-
resistant Gram-negative bacteria and is currently used as a last-line drug for treating severe …
resistant Gram-negative bacteria and is currently used as a last-line drug for treating severe …
Extraintestinal Pathogenic Escherichia coli: Virulence Factors and Antibiotic Resistance
The One Health approach emphasizes the importance of antimicrobial resistance (AMR) as
a major concern both in public health and in food animal production systems. As a general …
a major concern both in public health and in food animal production systems. As a general …
Colistin: an update on the antibiotic of the 21st century
S Biswas, JM Brunel, JC Dubus… - Expert review of anti …, 2012 - Taylor & Francis
The emergence of multidrug-resistant Gram-negative bacteria that cause nosocomial
infections is a growing problem worldwide. Colistin was first introduced in 1952 and was …
infections is a growing problem worldwide. Colistin was first introduced in 1952 and was …
Antibiotic Modulation of Capsular Exopolysaccharide and Virulence in Acinetobacter baumannii
E Geisinger, RR Isberg - PLoS pathogens, 2015 - journals.plos.org
Acinetobacter baumannii is an opportunistic pathogen of increasing importance due to its
propensity for intractable multidrug-resistant infections in hospitals. All clinical isolates …
propensity for intractable multidrug-resistant infections in hospitals. All clinical isolates …
Colistin in the 21st century
Because few, if any, new antibiotics with activity against multidrug-resistant Gram-negative
bacteria will be available within the next several years, it is essential that colistin is used in …
bacteria will be available within the next several years, it is essential that colistin is used in …
Masquerading microbial pathogens: capsular polysaccharides mimic host-tissue molecules
BF Cress, JA Englaender, W He… - FEMS microbiology …, 2014 - academic.oup.com
The increasing prevalence of antibiotic-resistant bacteria portends an impending
postantibiotic age, characterized by diminishing efficacy of common antibiotics and routine …
postantibiotic age, characterized by diminishing efficacy of common antibiotics and routine …
Bacterial strategies of resistance to antimicrobial peptides
Antimicrobial peptides (AMPs) are a key component of the host's innate immune system,
targeting invasive and colonizing bacteria. For successful survival and colonization of the …
targeting invasive and colonizing bacteria. For successful survival and colonization of the …
The promising potential of reverse vaccinology-based next-generation vaccine development over conventional vaccines against antibiotic-resistant bacteria
The clinical use of antibiotics has led to the emergence of multidrug-resistant (MDR)
bacteria, leading to the current antibiotic resistance crisis. To address this issue, next …
bacteria, leading to the current antibiotic resistance crisis. To address this issue, next …
Structure, biosynthesis, and function of bacterial capsular polysaccharides synthesized by ABC transporter-dependent pathways
LM Willis, C Whitfield - Carbohydrate research, 2013 - Elsevier
Bacterial capsules are formed primarily from long-chain polysaccharides with repeat-unit
structures. A given bacterial species can produce a range of capsular polysaccharides …
structures. A given bacterial species can produce a range of capsular polysaccharides …
Capsule polysaccharide is a bacterial decoy for antimicrobial peptides
E Llobet, JM Tomas, JA Bengoechea - Microbiology, 2008 - microbiologyresearch.org
Antimicrobial peptides (APs) are important host weapons against infections. Nearly all APs
are cationic and their microbicidal action is initiated through interactions with the anionic …
are cationic and their microbicidal action is initiated through interactions with the anionic …