The recent convergence between physics and biology has led many physicists to enter the
fields of cell and developmental biology. One of the most exciting areas of interest has been …

Kjær, Michael. Role of Extracellular Matrix in Adaptation of Tendon and Skeletal Muscle to
Mechanical Loading. Physiol Rev 84: 649–698, 2004; 10.1152/physrev. 00031.2003.—The …

The mechanism of action of acupuncture remains largely unknown. The reaction to
acupuncture needling known as 'de qi', widely viewed as essential to the therapeutic effect …

Cancer cells exist in a constantly evolving tissue microenvironment of diverse cell types
within a proteinaceous extracellular matrix. As tumors evolve, the physical forces within this …

Growth factors play a crucial role in information transfer between cells and their
microenvironment in tissue engineering and regeneration. They initiate their action by …

One of the most challenging problems in critical care medicine is the management of
patients with the acute respiratory distress syndrome. Increasing evidence from …

Mechanical forces are important regulators of connective tissue homeostasis. Our recent
experiments in vivo indicate that externally applied mechanical load can lead to the rapid …

Building of tissue, whether in the embryo or after injury in the adult, requires coordination of
several important cellular actions including fibrogenesis, proliferation, migration, contraction …

We studied the effect of cyclic mechanical stretching on the proliferation and collagen mRNA
expression and protein production of human patellar tendon fibroblasts under serum-free …

The biomechanical properties of connective tissues play fundamental roles in how
mechanical interactions of the body with its environment produce physical forces at the …