The accurate regulation of the microenvironment within the nervous system is one of the key
features characterizing complex organisms. To this end, neural tissue has to be physically …

Repetitive physical insults to the head, including those that elicit mild traumatic brain injury
(mTBI), are a known risk factor for a variety of neurodegenerative conditions including …

黑腹果蝇(Drosophila melanogaster) 是一种重要的模式生物, 因其生命周期短, 培养成本低,
突变体资源丰富, 基因操作相对简单等特点在生物学研究中具有独特的优势. 近些年 …

Head traumas are high-mortality pathologies that can disable. Traumatic brain injury (TBI) is
a heterogeneous disease containing brain damage caused by external effects. In the human …

The protein tau is involved in the pathology of neurodegeneration through development into
aggregates by abnormal hyperphosphorylation events. Tau is mostly expressed in neurons …

As an important model organism, Drosophila melanogaster has unique advantages in
biological research because of its short life span, low culture cost, rich mutant resources and …

The underlying molecular processes of aberrant protein expression in neurodegeneration
are intricate and multifaceted, with ribosome-associated quality control (RQC) emerging as a …