Tumor breaching the capsule of a lymph node is termed extranodal extension (ENE). It
reflects aggressiveness of a tumor, creates anatomic challenges for disease clearance, and …

Extranodal extension (ENE) is a very strong prognostic factor in head and neck squamous
cell carcinoma. However, significant variance in reported incidence of ENE suggests …

Objective Extranodal extension (ENE) is known to be associated with poor outcomes in
head and neck squamous cell carcinoma. The objective of this study is to examine the …

Background We compared the predictive ability of our proposed N classification with that of
the American Joint Committee on Cancer (AJCC) nodal (N) classification for oral cavity …

Purpose The presence of extranodal extension (ENE) conveys a poor prognosis in oral
cavity squamous cell carcinoma (OSCC); however, there is no consensus regarding whether …

Abstract Purpose Adenoid cystic carcinoma (AdCC) is generally slow growing but has highly
metastatic potential to distant organs. Several factors and biomarkers are associated with …

Background Oral cavity cancers, the second most common type in India, are responsible for
10% of the overall cancer burden. With a recurrence rate of 30% to 40% and a 5-year …

Background Oral cancer portends a significant cause of morbidity and mortality worldwide.
Cervical lymph node metastasis with extranodal extension (ENE) is associated with a poor …

Extranodal extension (ENE) is a pattern of cancer growth from within the lymph node (LN)
outward into perinodal tissues, critically defined by disruption and penetration of the tumor …

Background Whether extra-nodal extension (ENE+) and surgical margin positivity (margin+)
are poor prognostic factors in HPV-associated (HPV+) oropharyngeal carcinoma (OPC) …