Next-generation sequencing (NGS) technologies are increasingly being used to address a
diverse range of biological and epidemiological questions. The current understanding of …

Local and cross-border importation remain major challenges to malaria elimination and are
difficult to measure using traditional surveillance data. To address this challenge, we …

An essential step toward reconstructing pathogen transmission and answering
epidemiologically relevant questions from genomic data is obtaining pairwise genetic …

Unprecedented efforts in malaria control over the last 15 years have led to a substantial
decrease in both morbidity and mortality in most endemic settings. However, these …

Background To better understand transmission dynamics, we characterized Plasmodium
falciparum genetic diversity in Eswatini, where transmission is low and sustained by …

For a decade, the Southern and Central Africa International Center of Excellence for Malaria
Research has operated with local partners across study sites in Zambia and Zimbabwe that …

Background Genomic surveillance is crucial for monitoring malaria transmission and
understanding parasite adaptation to interventions. Zambia lacks prior nationwide efforts in …

Human movement impacts the spread and transmission of infectious diseases. Recently, a
large reservoir of Plasmodium falciparum malaria was identified in a semi-arid region of …

The successful implementation of pathogen genomic surveillance demands rapid, low-cost
genotyping solutions for tracking infections. Here we demonstrate the capacity of single …

Malaria elimination strategies are designed to more effectively identify and treat infected
individuals to interrupt transmission. One strategy, reactive screen-and-treat, starts with …