Mitochondrial dysfunction and oxidative stress in heart disease
Beyond their role as a cellular powerhouse, mitochondria are emerging as integral players
in molecular signaling and cell fate determination through reactive oxygen species (ROS) …
in molecular signaling and cell fate determination through reactive oxygen species (ROS) …
Mitochondrial dysfunction in pathophysiology of heart failure
B Zhou, R Tian - The Journal of clinical investigation, 2018 - Am Soc Clin Investig
Mitochondrial dysfunction has been implicated in the development of heart failure. Oxidative
metabolism in mitochondria is the main energy source of the heart, and the inability to …
metabolism in mitochondria is the main energy source of the heart, and the inability to …
Gut microbiota protects honey bees (Apis mellifera L.) against polystyrene microplastics exposure risks
Microplastic contamination is not only a pressing environmental concern in oceans, but also
terrestrial ecosystems. However, little is known about its potential impacts on pollinators …
terrestrial ecosystems. However, little is known about its potential impacts on pollinators …
[HTML][HTML] The role of reactive oxygen species in the pathophysiology of cardiovascular diseases and the clinical significance of myocardial redox
Acute and chronic excessive intracellular increase of reactive oxygen species (ROS) is
involved in the development and progression of cardiovascular diseases. ROS are by …
involved in the development and progression of cardiovascular diseases. ROS are by …
PTEN-inducible kinase 1 (PINK1)/Park6 is indispensable for normal heart function
Oxidative stress is caused by an imbalance between reactive oxygen species (ROS)
production and the ability of an organism to eliminate these toxic intermediates. Mutations in …
production and the ability of an organism to eliminate these toxic intermediates. Mutations in …
Lipid peroxidation in atherosclerotic cardiovascular diseases
E Gianazza, M Brioschi… - Antioxidants & redox …, 2021 - liebertpub.com
Significance: Atherosclerotic cardiovascular diseases (ACVDs) continue to be a primary
cause of mortality worldwide in adults aged 35–70 years, occurring more often in countries …
cause of mortality worldwide in adults aged 35–70 years, occurring more often in countries …
Selenium, selenoproteins, and heart failure: current knowledge and future perspective
AA Al-Mubarak, P van der Meer, N Bomer - Current heart failure reports, 2021 - Springer
Abstract Purpose of Review (Mal-) nutrition of micronutrients, like selenium, has great impact
on the human heart and improper micronutrient intake was observed in 30–50% of patients …
on the human heart and improper micronutrient intake was observed in 30–50% of patients …
Daily rhythms of phytomelatonin signaling modulate diurnal stomatal closure via regulating reactive oxygen species dynamics in Arabidopsis
D Li, J Wei, Z Peng, W Ma, Q Yang… - Journal of Pineal …, 2020 - Wiley Online Library
Melatonin is a well‐studied neurohormone oscillating in a 24‐h cycle in vertebrates.
Phytomelatonin is widespread in plant kingdom, but it remains elusive whether this newly …
Phytomelatonin is widespread in plant kingdom, but it remains elusive whether this newly …
The ubiquitin E3 ligase TRAF6 exacerbates pathological cardiac hypertrophy via TAK1-dependent signalling
YX Ji, P Zhang, XJ Zhang, YC Zhao, KQ Deng… - Nature …, 2016 - nature.com
Tumour necrosis factor receptor-associated factor 6 (TRAF6) is a ubiquitin E3 ligase that
regulates important biological processes. However, the role of TRAF6 in cardiac hypertrophy …
regulates important biological processes. However, the role of TRAF6 in cardiac hypertrophy …
NADPH oxidases in heart failure: poachers or gamekeepers?
M Zhang, A Perino, A Ghigo, E Hirsch… - Antioxidants & redox …, 2013 - liebertpub.com
Significance: Oxidative stress is involved in the pathogenesis of heart failure but clinical
antioxidant trials have been unsuccessful. This may be because effects of reactive oxygen …
antioxidant trials have been unsuccessful. This may be because effects of reactive oxygen …