The origin of vertebrates was accompanied by the advent of a novel cell type: the neural
crest. Emerging from the central nervous system, these cells migrate to diverse locations and …

The neural crest is a multipotent and migratory cell type that forms transiently in the
developing vertebrate embryo. These cells emerge from the central nervous system, migrate …

The cranial neural crest generates a huge diversity of derivatives, including the bulk of
connective and skeletal tissues of the vertebrate head. How neural crest cells acquire such …

Major differences in facial morphology distinguish vertebrate species. Variation of facial
traits underlies the uniqueness of human individuals, and abnormal craniofacial …

The neural crest (NC) yields pluripotent cells endowed with migratory properties. They give
rise to neurons, glia, melanocytes and endocrine cells, and to diversemesenchymal' …

The major mineralized tissues are bone and teeth, which share several mechanisms
governing their development and mineralization. This crossover includes the hormones that …

Head development in vertebrates involves a complex series of molecular and
morphogenetic events that generate a coordinated pattern of cartilages, bones and nerves …

Bone is an evolutionary novelty of vertebrates, likely to have first emerged as part of
ancestral dermal armor that consisted of osteogenic and odontogenic components. Whether …

In the vertebrate embryo, the neural crest forms transiently in the dorsal neural primordium to
yield migratory cells that will invade nearly all tissues and later, will differentiate into bones …

The neural crest (NC) is a major contributor to the vertebrate craniofacial skeleton, detailed
in model organisms through embryological and genetic approaches, most notably in chick …