Cartilage and the bordering subchondral bone form a functionally active regulatory interface
with a prominent role in osteoarthritis pathways. The Wnt and the OPG-RANKL-RANK …

Background: While research on Virtual Reality's potential for education continues to
advance, research on its support for Collaborative Learning is small in scope. With remote …

As the vertebrate skeleton develops it progresses from a solely cartilaginous scaffold to a
mineralized bony skeleton. The cells that build up the skeleton, the chondrocytes and …

Bone-forming osteoblasts have been a cornerstone of bone biology for more than a century.
Most research toward bone biology and bone diseases center on osteoblasts. Overlooked …

The vertebrate musculoskeletal system is known to be formed by mesenchymal stem cells
condensing into tissue elements, which then differentiate into cartilage, bone …

This study investigates if the application of bone marrow-derived mesenchymal stem cells
(BM-MSCs) loaded 3D-printed scaffolds could improve rotator cuff repair. The polylactic-co …

Hypertrophic chondrocytes are found at unique locations at the junction of skeletal tissues,
cartilage growth plate, articular cartilage, enthesis and intervertebral discs. Their role in the …

Abstract Purpose of Review The goal of the review is to summarize the current knowledge
on the process of chondrocyte-to-osteoblast transdifferentiation during endochondral bone …

Although recent lineage studies strongly support a chondrocyte-to-osteoblast differentiation
continuum, the biological significance and molecular basis remain undetermined. In silico …

ABSTRACT DMP1 (dentin matrix protein 1) is an extracellular matrix protein highly
expressed in bones. Studies of Dmp1 knockout (KO) mice led to the discovery of a rare …