The Na+/Ca2+ exchanger, an ion transport protein, is expressed in the plasma membrane
(PM) of virtually all animal cells. It extrudes Ca2+ in parallel with the PM ATP-driven Ca2+ …

Ca2+ is an essential ion in all organisms, where it plays a crucial role in processes ranging
from the formation and maintenance of the skeleton to the temporal and spatial regulation of …

The distal tubule of the mammalian kidney, defined as the region between the macula densa
and the collecting duct, is morphologically and functionally heterogeneous. This …

The distal tubule of the mammalian kidney can be defined as the nephron segment between
the macula densa region and the cortical collecting tubule. It comprises several …

The kidneys play a vital role in mineral homeostasis. In this review, the handling of calcium
and the methods currently applied to measuring its intracellular concentration are discussed …

The intestinal absorption of Ca 2+ occurs by both a saturable, transcellular process and a
non-saturable, paracellular path. The transcellular path is a multistep process, comprised of …

The plasma membrane Ca2+-ATPase (PMCA) and the NCX1 Na+/Ca2+ exchanger regulate
intracellular Ca2+ concentrations and mediate Ca2+ efflux in absorptive epithelial cells. We …

Calcium is the most abundant cation in human beings. A 70 kg man contains about 2 kg
calcium of which more than 99% occurs in bone. Under normal conditions, daily dietary …

Calcium (re) absorption occurs in epithelia, including the intestine, kidney, mammary glands,
placenta and gills (in the case of fish). 2. Calcium is transported across epithelia by two …

In the present study, the polymerase chain reaction (PCR) and library screening were used
to clone a cDNA for a rabbit kidney Na (+)-Ca2+ exchanger on the basis of homology with …