A current review of cypermethrin-induced neurotoxicity and nigrostriatal dopaminergic neurodegeneration

A Kumar Singh, M Nath Tiwari… - Current …, 2012 - ingentaconnect.com
Cypermethrin, a class II pyrethroid pesticide, is used to control insects in the household and
agricultural fields. Despite beneficial roles, its uncontrolled and repetitive applications lead …

Developmental toxicity of cypermethrin in embryo-larval stages of zebrafish

X Shi, A Gu, G Ji, Y Li, J Di, J Jin, F Hu, Y Long, Y Xia… - Chemosphere, 2011 - Elsevier
Cypermethrin, a type II pyrethroid insecticide, is widely used throughout the world in
agriculture, forestry, horticulture and homes. Though the neurotoxicity of cypermethrin has …

Post weaning social isolation influences spatial cognition, prefrontal cortical synaptic plasticity and hippocampal potassium ion channels in Wistar rats

MN Quan, YT Tian, KH Xu, T Zhang, Z Yang - Neuroscience, 2010 - Elsevier
Post weaning isolation-reared rats show deficits in learning and memory, which are also
seen in many psychiatric disorders like schizophrenia. The present study utilized behavioral …

Assessing the Risks of Pesticide Exposure: Implications for Endocrine Disruption and Male Fertility

C Uwamahoro, JH Jo, SI Jang, EJ Jung… - International Journal of …, 2024 - mdpi.com
Pesticides serve as essential tools in agriculture and public health, aiding in pest control and
disease management. However, their widespread use has prompted concerns regarding …

Systematic development of a simultaneous determination of plastic particle identity and adsorbed organic compounds by thermodesorption–pyrolysis GC/MS (TD-Pyr …

J Reichel, J Graßmann, T Letzel, JE Drewes - Molecules, 2020 - mdpi.com
Micro-, submicro-and nanoplastic particles are increasingly regarded as vectors for trace
organic chemicals. In order to determine adsorbed trace organic chemicals on polymers, it …

Effect of titanium dioxide nanoparticles on the bioavailability and neurotoxicity of cypermethrin in zebrafish larvae

M Li, Q Wu, Q Wang, D Xiang, G Zhu - Aquatic Toxicology, 2018 - Elsevier
In aquatic environment, the presence of nanoparticles (NPs) has been reported to modify the
bioavailability and toxicity of the organic toxicants. Nevertheless, the combined toxicity of …

Nano-CuO impairs spatial cognition associated with inhibiting hippocampal long-term potentiation via affecting glutamatergic neurotransmission in rats

X Li, W Sun, L An - Toxicology and Industrial Health, 2018 - journals.sagepub.com
Manufactured metal nanoparticles and their applications are continuously expanding
because of their unique characteristics while their increasing use may predispose to …

Stereoisomeric selectivity in the endocrine-disrupting potential of cypermethrin using in vitro, in vivo, and in silico assays

Q Zhang, S Yu, X Chen, L Fu, W Dai, S Gu - Journal of Hazardous Materials, 2021 - Elsevier
Despite the ubiquity of cypermethrin (CYP) stereoisomers in environment biota, the
stereoisomeric selectivity of endocrine-disrupting potency of α-CYP, β-CYP, and θ-CYP has …

Inhibition of voltage-gated calcium channels as common mode of action for (mixtures of) distinct classes of insecticides

M Meijer, MML Dingemans… - Toxicological …, 2014 - academic.oup.com
Humans are exposed to distinct structural classes of insecticides with different neurotoxic
modes of action. Because calcium homeostasis is essential for proper neuronal function and …

Proteomic profiling reveals neuronal ion channel dysregulation and cellular responses to DNA damage-induced cell cycle arrest and senescence in human …

K Promthep, C Nopparat, S Mukda, S Pannengpetch… - Neurotoxicology, 2022 - Elsevier
Cypermethrin (CYP), a synthetic pyrethroid of class II, is widely used as a pesticide
worldwide. The primary target of cypermethrin is a voltage-gated sodium channel. The …