Effects of exercise on HDL functionality

JJ Ruiz-Ramie, JL Barber… - Current opinion in …, 2019 - journals.lww.com
There is mixed evidence that regular aerobic exercise improves cholesterol efflux capacity,
with recent research suggesting an exercise dose threshold needs to be exceeded to …

High density lipoprotein cholesterol efflux capacity and atherosclerosis in cardiovascular disease: pathophysiological aspects and pharmacological perspectives

MP Adorni, N Ronda, F Bernini, F Zimetti - Cells, 2021 - mdpi.com
Over the years, the relationship between high-density lipoprotein (HDL) and atherosclerosis,
initially highlighted by the Framingham study, has been revealed to be extremely complex …

HDL in the 21st century: a multifunctional roadmap for future HDL research

A Rohatgi, M Westerterp, A Von Eckardstein… - Circulation, 2021 - Am Heart Assoc
Low high-density lipoprotein cholesterol (HDL-C) characterizes an atherogenic dyslipidemia
that reflects adverse lifestyle choices, impaired metabolism, and increased cardiovascular …

[HTML][HTML] Structure-function relationships of HDL in diabetes and coronary heart disease

M Cardner, M Yalcinkaya, S Goetze, E Luca, M Balaz… - JCI insight, 2020 - ncbi.nlm.nih.gov
High-density lipoproteins (HDL) contain hundreds of lipid species and proteins and exert
many potentially vasoprotective and antidiabetogenic activities on cells. To resolve structure …

Lipidomic approaches to study HDL metabolism in patients with central obesity diagnosed with metabolic syndrome

G Mocciaro, S D'amore, B Jenkins, R Kay… - International Journal of …, 2022 - mdpi.com
The metabolic syndrome (MetS) is a cluster of cardiovascular risk factors characterised by
central obesity, atherogenic dyslipidaemia, and changes in the circulating lipidome; the …

Moderate‐and high‐intensity exercise improves lipoprotein profile and cholesterol efflux capacity in healthy young men

KM Stanton, V Kienzle, DLM Dinnes… - Journal of the …, 2022 - Am Heart Assoc
Background Exercise is associated with a reduced risk of cardiovascular disease. Increased
high‐density lipoprotein cholesterol (HDL‐C) levels are thought to contribute to these …

Highlighting residual atherosclerotic cardiovascular disease risk

Y Matsuura, JE Kanter, KE Bornfeldt - … , thrombosis, and vascular …, 2019 - Am Heart Assoc
e2 Arterioscler Thromb Vasc Biol January 2019 lipoprotein remnant particles can penetrate
and accumulate in the subendothelial arterial space and induce local and systemic …

Molecular characterization of plasma HDL, LDL, and VLDL lipids cargos from atherosclerotic patients with advanced carotid lesions: a preliminary report

G Nieddu, E Michelucci, M Formato… - International Journal of …, 2022 - mdpi.com
Carotid atherosclerosis represents a relevant healthcare problem, since unstable plaques
are responsible for approximately 15% of neurologic events, namely transient ischemic …

Coronary artery disease

H Agrawal, HK Choy, J Liu, M Auyoung… - … , and vascular biology, 2020 - Am Heart Assoc
In the past decade, remarkable strides have been made in understanding the genetics of
cardiovascular disease (CVD). McPherson1 demonstrated that the genetic architecture of …

Rethinking good cholesterol: a clinicians' guide to understanding HDL

AS Xiang, BA Kingwell - The Lancet Diabetes & Endocrinology, 2019 - thelancet.com
Low HDL cholesterol dyslipidaemia affects about half of people with type 2 diabetes and
represents a major independent risk factor for atherosclerotic cardiovascular disease. The" …