Anti‐inflammatory therapies in myocardial infarction: failures, hopes and challenges
S Huang, NG Frangogiannis - British journal of pharmacology, 2018 - Wiley Online Library
In the infarcted heart, the damage‐associated molecular pattern proteins released by
necrotic cells trigger both myocardial and systemic inflammatory responses. Induction of …
necrotic cells trigger both myocardial and systemic inflammatory responses. Induction of …
Inflammation as a therapeutic target in myocardial infarction: learning from past failures to meet future challenges
A Saxena, I Russo, NG Frangogiannis - Translational Research, 2016 - Elsevier
In the infarcted myocardium, necrotic cardiomyocytes release danger signals, activating an
intense inflammatory response. Inflammatory pathways play a crucial role in regulation of a …
intense inflammatory response. Inflammatory pathways play a crucial role in regulation of a …
Use of a supramolecular polymeric hydrogel as an effective post-operative pericardial adhesion barrier
LM Stapleton, AN Steele, H Wang… - Nature biomedical …, 2019 - nature.com
Post-operative adhesions form as a result of normal wound healing processes following any
type of surgery. In cardiac surgery, pericardial adhesions are particularly problematic during …
type of surgery. In cardiac surgery, pericardial adhesions are particularly problematic during …
[HTML][HTML] A unique collateral artery development program promotes neonatal heart regeneration
Collateral arteries are an uncommon vessel subtype that can provide alternate blood flow to
preserve tissue following vascular occlusion. Some patients with heart disease develop …
preserve tissue following vascular occlusion. Some patients with heart disease develop …
Injectable decellularized extracellular matrix hydrogel containing stromal cell-derived factor 1 promotes transplanted cardiomyocyte engraftment and functional …
K Wu, Y Wang, H Yang, Y Chen, K Lu… - … Applied Materials & …, 2023 - ACS Publications
Transplantation of exogenous cardiomyocytes (CMs) is a hopeful method to treat myocardial
infarction (MI). However, its clinical application still remains challenging due to low retention …
infarction (MI). However, its clinical application still remains challenging due to low retention …
Vascularization of three-dimensional engineered tissues for regenerative medicine applications
Engineering of three-dimensional (3D) tissues is a promising approach for restoring
diseased or dysfunctional myocardium with a functional replacement. However, a major …
diseased or dysfunctional myocardium with a functional replacement. However, a major …
Chemokines in myocardial infarction
B Chen, NG Frangogiannis - Journal of cardiovascular translational …, 2021 - Springer
In the infarcted myocardium, cardiomyocyte necrosis triggers an intense inflammatory
reaction that not only is critical for cardiac repair, but also contributes to adverse remodeling …
reaction that not only is critical for cardiac repair, but also contributes to adverse remodeling …
An innovative biologic system for photon-powered myocardium in the ischemic heart
JE Cohen, AB Goldstone, MJ Paulsen, Y Shudo… - Science …, 2017 - science.org
Coronary artery disease is one of the most common causes of death and disability, afflicting
more than 15 million Americans. Although pharmacological advances and revascularization …
more than 15 million Americans. Although pharmacological advances and revascularization …
State-of-the-art methods for evaluation of angiogenesis and tissue vascularization: a scientific statement from the American Heart Association
M Simons, K Alitalo, BH Annex, HG Augustin… - Circulation …, 2015 - Am Heart Assoc
The American Heart Association makes every effort to avoid any actual or potential conflicts
of interest that may arise as a result of an outside relationship or a personal, professional, or …
of interest that may arise as a result of an outside relationship or a personal, professional, or …
3D and 4D bioprinting of the myocardium: current approaches, challenges, and future prospects
CS Ong, L Nam, K Ong, A Krishnan… - BioMed research …, 2018 - Wiley Online Library
3D and 4D bioprinting of the heart are exciting notions in the modern era. However,
myocardial bioprinting has proven to be challenging. This review outlines the methods …
myocardial bioprinting has proven to be challenging. This review outlines the methods …