The metaphor of 'genomic islands of speciation'was first used to describe heterogeneous
differentiation among loci between the genomes of closely related species. The biological …

Population genetics theory supplies powerful predictions about how natural selection
interacts with genetic linkage to sculpt the genomic landscape of nucleotide polymorphism …

Recombination is a fundamental biological process with profound evolutionary implications.
Theory predicts that recombination increases the effectiveness of selection in natural …

Estimating fine-scale recombination maps of Drosophila from population genomic data is a
challenging problem, in particular because of the high background recombination rate. In …

The process of evolution at a given site in the genome can be influenced by the action of
selection at other sites, especially when these are closely linked to it. Such selection …

Over the past four decades, the predominant view of molecular evolution saw little
connection between natural selection and genome evolution, assuming that the functionally …

Under the neutral theory, genetic diversity is expected to increase with population size.
While comparative analyses have consistently failed to find strong relationships between …

Population genomic studies are beginning to provide a more comprehensive view of
dynamic genome-scale processes in evolution. Patterns of genomic architecture, such as …

The genetic variation that occurs naturally in a population is a powerful resource for studying
how genotype affects phenotype. Each allele is a perturbation of the biological system, and …

Despite their importance to successful meiosis and various evolutionary processes, meiotic
recombination rates sometimes vary within species or between closely related species. For …