Targeting metastatic cancer
K Ganesh, J Massagué - Nature medicine, 2021 - nature.com
Despite recent therapeutic advances in cancer treatment, metastasis remains the principal
cause of cancer death. Recent work has uncovered the unique biology of metastasis …
cause of cancer death. Recent work has uncovered the unique biology of metastasis …
Characterisation and classification of oligometastatic disease: a European Society for Radiotherapy and Oncology and European Organisation for Research and …
M Guckenberger, Y Lievens, AB Bouma… - The Lancet …, 2020 - thelancet.com
Oligometastatic disease has been proposed as an intermediate state between localised and
systemically metastasised disease. In the absence of randomised phase 3 trials, early …
systemically metastasised disease. In the absence of randomised phase 3 trials, early …
Uterine neoplasms, version 1.2023, NCCN clinical practice guidelines in oncology
Adenocarcinoma of the endometrium (also known as endometrial cancer, or more broadly
as uterine cancer or carcinoma of the uterine corpus) is the most common malignancy of the …
as uterine cancer or carcinoma of the uterine corpus) is the most common malignancy of the …
ESGO/ESTRO/ESP guidelines for the management of patients with endometrial carcinoma
N Concin, X Matias-Guiu, I Vergote, D Cibula… - International Journal of …, 2021 - ijgc.bmj.com
A European consensus conference on endometrial carcinoma was held in 2014 to produce
multi-disciplinary evidence-based guidelines on selected questions. Given the large body of …
multi-disciplinary evidence-based guidelines on selected questions. Given the large body of …
[HTML][HTML] Stereotactic ablative radiotherapy for the comprehensive treatment of oligometastatic cancers: long-term results of the SABR-COMET phase II randomized trial
PURPOSE The oligometastatic paradigm hypothesizes that patients with a limited number of
metastases may achieve long-term disease control, or even cure, if all sites of disease can …
metastases may achieve long-term disease control, or even cure, if all sites of disease can …
Outcomes of observation vs stereotactic ablative radiation for oligometastatic prostate cancer: the ORIOLE phase 2 randomized clinical trial
Importance Complete metastatic ablation of oligometastatic prostate cancer may provide an
alternative to early initiation of androgen deprivation therapy (ADT). Objective To determine …
alternative to early initiation of androgen deprivation therapy (ADT). Objective To determine …
[HTML][HTML] Randomized phase II trial of nivolumab with stereotactic body radiotherapy versus nivolumab alone in metastatic head and neck squamous cell carcinoma
PURPOSE The objective response rate (ORR) for single-agent anti–programmed death
receptor 1 (anti–PD-1) therapy is modest in patients with metastatic or recurrent head and …
receptor 1 (anti–PD-1) therapy is modest in patients with metastatic or recurrent head and …
[HTML][HTML] Defining oligometastatic disease from a radiation oncology perspective: An ESTRO-ASTRO consensus document
Y Lievens, M Guckenberger, D Gomez, M Hoyer… - Radiotherapy and …, 2020 - Elsevier
Background Recognizing the rapidly increasing interest and evidence in using metastasis-
directed radiotherapy (MDRT) for oligometastatic disease (OMD), ESTRO and ASTRO …
directed radiotherapy (MDRT) for oligometastatic disease (OMD), ESTRO and ASTRO …
[HTML][HTML] Management of patients with advanced prostate cancer: report of the advanced prostate cancer consensus conference 2019
Background Innovations in treatments, imaging, and molecular characterisation in advanced
prostate cancer have improved outcomes, but there are still many aspects of management …
prostate cancer have improved outcomes, but there are still many aspects of management …
Definitive radiotherapy in lieu of systemic therapy for oligometastatic renal cell carcinoma: a single-arm, single-centre, feasibility, phase 2 trial
Background The role of radiotherapy in metastatic renal cell carcinoma is controversial. We
prospectively tested the feasibility and efficacy of radiotherapy to defer systemic therapy for …
prospectively tested the feasibility and efficacy of radiotherapy to defer systemic therapy for …