miR-1247-3p mediates apoptosis of cerebral neurons by targeting caspase-2 in stroke

R Zhang, W Zhou, Z Yu, L Yang, G Liu, H Yu, Q Zhou… - Brain research, 2019 - Elsevier
Brain stroke is one of the leading causes of death worldwide. We explored a potential stroke-
related role for a newly found microRNA, miR-1247-3p, and one of its target genes, caspase …

[HTML][HTML] Neuroprotective effect of Src kinase in hypoxia-ischemia: A systematic review

P Christidis, A Vij, S Petousis… - Frontiers in …, 2022 - frontiersin.org
Background Hypoxic-ischemic encephalopathy (HIE) is a major cause of neonatal morbidity
and mortality worldwide. While the application of therapeutic hypothermia has improved …

[HTML][HTML] Neurodevelopment: parental influences, in utero exposures, and genetics

SG Tractenberg, SM Reinhard… - Frontiers in …, 2024 - frontiersin.org
The development of the central nervous system is subject to a broad range of disruptions
both environmental and genetic in nature. These disruptions to neurodevelopmental …

[HTML][HTML] Transcriptome profiling of caspase-2 deficient EμMyc and Th-MYCN mouse tumors identifies distinct putative roles for caspase-2 in neuronal differentiation …

L Dorstyn, E Hackett-Jones, A Nikolic, MD Norris… - Cell death & …, 2019 - nature.com
Caspase-2 is a highly conserved cysteine protease with roles in apoptosis and tumor
suppression. Our recent findings have also demonstrated that the tumor suppression …

[HTML][HTML] 三磷酸腺苷脂质体鼻用凝胶制备及其抗缺氧作用

欧歌, 马金秋, 朱林, 李瑞滕, 李欣, 杜丽娜 - 药学学报, 2020 - html.rhhz.net
制备三磷酸腺苷(adenosine triphosphate, ATP) 脂质体, 评价其对缺氧性脑损伤的治疗作用.
采用离子对薄膜分散法制备ATP 脂质体, 其最优处方: 三磷酸腺苷二钠, 十六烷基三甲基溴化铵 …