Optogenetics for light control of biological systems

V Emiliani, E Entcheva, R Hedrich… - Nature Reviews …, 2022 - nature.com
Optogenetic techniques have been developed to allow control over the activity of selected
cells within a highly heterogeneous tissue, using a combination of genetic engineering and …

Organic Bioelectronics for In Vitro Systems

C Pitsalidis, AM Pappa, AJ Boys, Y Fu… - Chemical …, 2021 - ACS Publications
Bioelectronics have made strides in improving clinical diagnostics and precision medicine.
The potential of bioelectronics for bidirectional interfacing with biology through continuous …

Cardiogenic control of affective behavioural state

B Hsueh, R Chen, YJ Jo, D Tang, M Raffiee, YS Kim… - Nature, 2023 - nature.com
Emotional states influence bodily physiology, as exemplified in the top-down process by
which anxiety causes faster beating of the heart,–. However, whether an increased heart …

Photocatalytic superoxide radical generator that induces pyroptosis in cancer cells

L Yu, Y Xu, Z Pu, H Kang, M Li… - Journal of the …, 2022 - ACS Publications
Pyroptosis, a newly characterized form of immunogenic cell death, is attracting increasing
attention as a promising approach to cancer immunotherapy. However, biocompatible …

Tether-free photothermal deep-brain stimulation in freely behaving mice via wide-field illumination in the near-infrared-II window

X Wu, Y Jiang, NJ Rommelfanger, F Yang… - Nature Biomedical …, 2022 - nature.com
Neural circuitry is typically modulated via invasive brain implants and tethered optical fibres
in restrained animals. Here we show that wide-field illumination in the second near-infrared …

All-optical physiology resolves a synaptic basis for behavioral timescale plasticity

LZ Fan, DK Kim, JH Jennings, H Tian, PY Wang… - Cell, 2023 - cell.com
Learning has been associated with modifications of synaptic and circuit properties, but the
precise changes storing information in mammals have remained largely unclear. We …

Structural basis for channel conduction in the pump-like channelrhodopsin ChRmine

KE Kishi, YS Kim, M Fukuda, M Inoue, T Kusakizako… - Cell, 2022 - cell.com
ChRmine, a recently discovered pump-like cation-conducting channelrhodopsin, exhibits
puzzling properties (large photocurrents, red-shifted spectrum, and extreme light sensitivity) …

Ectopic expression of a mechanosensitive channel confers spatiotemporal resolution to ultrasound stimulations of neurons for visual restoration

S Cadoni, C Demené, I Alcala, M Provansal… - Nature …, 2023 - nature.com
Remote and precisely controlled activation of the brain is a fundamental challenge in the
development of brain–machine interfaces for neurological treatments. Low-frequency …

Silicon photonics for the visible and near-infrared spectrum

JKS Poon, A Govdeli, A Sharma, X Mu… - Advances in Optics …, 2024 - opg.optica.org
Emerging applications in quantum information, microscopy, biosensing, depth sensing, and
augmented reality demand miniaturized components in the visible (VIS) and near-infrared …

Nanotransducer-enabled deep-brain neuromodulation with NIR-II light

X Wu, F Yang, S Cai, K Pu, G Hong - ACS nano, 2023 - ACS Publications
The second near-infrared window (NIR-II window), which ranges from 1000 to 1700 nm in
wavelength, exhibits distinctive advantages of reduced light scattering and thus deep …