The human factor H protein family–an update

N Sándor, AE Schneider, AT Matola… - Frontiers in …, 2024 - frontiersin.org
Complement is an ancient and complex network of the immune system and, as such, it plays
vital physiological roles, but it is also involved in numerous pathological processes. The …

Evaluating the clinical utility of measuring levels of factor H and the related proteins

P Banerjee, BRJ Veuskens, EG de Jorge, M Józsi… - Molecular …, 2022 - Elsevier
After years of disappointing clinical results, the tide has finally changed and complement
targeted-therapies have become a validated and accepted treatment option for several …

Mechanisms by which Factor H protects Trypanosoma cruzi from the alternative pathway of complement

SS Menon, G Ramirez-Toloza, KL Wycoff… - Frontiers in …, 2024 - frontiersin.org
Chagas disease, a chronic disabling disease caused by the protozoan Trypanosoma cruzi,
has no standardized treatment or preventative vaccine. The infective trypomastigote form of …