Umbilical cord blood: an undervalued and underutilized resource in allogeneic hematopoietic stem cell transplant and novel cell therapy applications

PA Shi, LL Luchsinger, JM Greally… - Current opinion in …, 2022 - journals.lww.com
The potential of allogeneic UCB for HCT and novel cell-based therapies is undervalued and
underutilized. The inventory of high-quality UCB units available from public cord blood …

[HTML][HTML] Equitable access to cell and gene therapies in South Africa: opportunities and hurdles

CL Hendricks, M Alessandrini, MS Pepper - Gene Therapy, 2023 - nature.com
At present, more than 1200 cell and gene therapy (CGT) clinical trials are ongoing [1], and
up to 50 such treatments are expected to be clinically available by 2030 [2]. A major …

Haematopoietic stem-cell transplantation in an HIV endemic area: time to consider donors exposed to or living with HIV

CL Hendricks, J Mellet, C Durandt, D Brittain… - The Lancet …, 2023 - thelancet.com
South Africa has more than 8 million people living with HIV. However, the number of patients
undergoing haematopoietic stem-cell transplantation (HSCT) in South Africa is far below the …

[HTML][HTML] Regenerative medicines: A new regulatory paradigm for South Africa

IM Viljoen, CL Hendricks, HL Malherbe, MS Pepper - Biochimie, 2022 - Elsevier
Clinicians are increasingly using regenerative medicines to repair, replace, regenerate or
rejuvenate lost, damaged or diseased genes, cells, tissues or organs. In South Africa …

When cells become medicines: A South African perspective

IM Viljoen, MS Pepper - South African Medical Journal, 2021 - journals.co.za
The discovery of human leucocyte antigen (HLA), serological matching and HLA-typing
techniques, combined with the development of immunosuppressive medicines and …

[HTML][HTML] Childhood aplastic anaemia with paroxysmal nocturnal haemoglobinuria clones: A retrospective single-centre study in South Africa

CL Hendricks, A Naidoo, R Thejpal, N Rapiti… - African Journal of …, 2022 - scielo.org.za
HENDRICKS, Candice L. et al. Childhood aplastic anaemia with paroxysmal nocturnal
haemoglobinuria clones: A retrospective single-centre study in South Africa. Afr. J. Lab …