Immunoglobulin E (IgE) antibodies are well known for their role in mediating allergic
reactions, and their powerful effector functions activated through binding to Fc receptors …

Cutaneous T-cell lymphomas (CTCL) are characterized by the presence of chronically
inflamed skin lesions containing malignant T cells. Early disease presents as limited skin …

Background: Mycosis fungoides (MF) and Sezary Syndrome (SS) are the most common
cutaneous T-cell lymphomas. It has been hypothesized that the interaction between the …

Primary cutaneous T-cell lymphomas (PCTCL) are the most common types of cutaneous
lymphomas, with Mycosis fungoides as the most frequent subtype. Besides early stages …

The signal transducer and activator of transcription 6 (STAT6) is a critical up-stream
mediator of interleukin-13 (IL-13) and IL-4 signaling and is constitutively activated in …

Sézary syndrome and erythrodermic mycosis fungoides have been recognized as part of a
broader spectrum of erythrodermic cutaneous T-cell lymphoma (E-CTCL). Atopic dermatitis …

Glioblastoma multiforme (GBM) is the most common primary brain tumor in adults. The
development of this malignant glial lesion involves a multi-faceted process that results in a …

Results There was a statistically significant positive correlation between high b2-
microglobulin levels and the advanced stage of disease (p< 0.001). The older group of …

Cutaneous T-cell lymphomas are a heterogenous group of lymphomas that cause various
skin manifestations. Severe pruritus occurs frequently in cutaneous T-cell lymphoma and …

Tumor cells in cutaneous T-cell lymphoma express limited numbers of chemokine receptors.
We investigated the expression patterns of CXCR3, CCR3, CCR4 and CCR10 in mycosis …