Multimorbidity and depression: a systematic review and meta-analysis

JR Read, L Sharpe, M Modini, BF Dear - Journal of affective disorders, 2017 - Elsevier
Background Multimorbidity, the presence of two or more chronic conditions, is increasingly
common and complicates the assessment and management of depression. The aim was to …

Multimorbidity patterns: a systematic review

A Prados-Torres, A Calderón-Larrañaga… - Journal of clinical …, 2014 - Elsevier
Objectives The aim of this review was to identify studies on patterns of associative
multimorbidity, defined as the nonrandom association between diseases, focusing on the …

Assessing and measuring chronic multimorbidity in the older population: a proposal for its operationalization

A Calderón-Larrañaga, DL Vetrano… - … Series A: Biomedical …, 2017 - academic.oup.com
Background Although the definition of multimorbidity as “the simultaneous presence of two
or more chronic diseases” is well established, its operationalization is not yet agreed. This …

Aging with multimorbidity: a systematic review of the literature

A Marengoni, S Angleman, R Melis… - Ageing research …, 2011 - Elsevier
A literature search was carried out to summarize the existing scientific evidence concerning
occurrence, causes, and consequences of multimorbidity (the coexistence of multiple …

Epidemiology and impact of multimorbidity in primary care: a retrospective cohort study

C Salisbury, L Johnson, S Purdy, JM Valderas… - British Journal of …, 2011 - bjgp.org
Background In developed countries, primary health care increasingly involves the care of
patients with multiple chronic conditions, referred to as multimorbidity. Aim To describe the …

Guidelines for people not for diseases: the challenges of applying UK clinical guidelines to people with multimorbidity

LD Hughes, MET McMurdo, B Guthrie - Age and ageing, 2013 - academic.oup.com
Background: currently one of the major challenges facing clinical guidelines is
multimorbidity. Current guidelines are not designed to consider the cumulative impact of …

Examining different measures of multimorbidity, using a large prospective cross-sectional study in Australian general practice

C Harrison, H Britt, G Miller, J Henderson - BMJ open, 2014 - bmjopen.bmj.com
Objectives Prevalence estimates of multimorbidity vary widely due to inconsistent definitions
and measurement methods. This study examines the independent effects on prevalence …

Multimorbidity and comorbidity revisited: refining the concepts for international health research

K Nicholson, TT Makovski, LE Griffith, P Raina… - Journal of clinical …, 2019 - Elsevier
While both terms focus on the occurrence of multiple chronic conditions within the same
individual, the term “comorbidity” refers to the combined effects of additional conditions in …

Do replicable profiles of multimorbidity exist? Systematic review and synthesis

L Busija, K Lim, C Szoeke, KM Sanders… - European journal of …, 2019 - Springer
This systematic review aimed to synthesise multimorbidity profiling literature to identify
replicable and clinically meaningful groupings of multimorbidity. We searched six electronic …

Multiple diseases and polypharmacy in the elderly: challenges for the internist of the third millennium

A Nobili, S Garattini, PM Mannucci - Journal of comorbidity, 2011 - journals.sagepub.com
The pattern of patients admitted to internal medicine wards has dramatically changed in the
last 20–30 years. Elderly people are now the most rapidly growing proportion of the patient …