Metabolites produced by commensal gut microbes impact host health through their
recognition by the immune system and their influence on numerous metabolic pathways …

The intestinal microbiota plays a crucial role in influencing the development of host
immunity, and in turn the immune system also acts to regulate the microbiota through …

Sphingolipids are structural membrane components and important eukaryotic signaling
molecules. Sphingolipids regulate inflammation and immunity and were recently identified …

Gut microbes are linked to host metabolism, but specific mechanisms remain to be
uncovered. Ceramides, a type of sphingolipid (SL), have been implicated in the …

Odoribacter splanchnicus, belonging to the order Bacteroidales, is a common, short-chain
fatty acid producing member of the human intestinal microbiota. A decreased abundance of …

Bioactive sphingolipids—ceramide, sphingosine, and their respective 1-phosphates (C1P
and S1P)—are signaling molecules serving as intracellular second messengers. Moreover …

Nitrogen-fixing cyanobacteria from the order Nostocales are able to establish symbiotic
relationships with diverse plant species. They are promiscuous symbionts, as the same …

Background There is general consensus that consumption of dietary fermentable fiber
improves cardiometabolic health, in part by promoting mutualistic microbes and by …

Dietary habits have drastically changed over the last decades in Western societies. The
Western diet, rich in saturated fatty acids (SFA), trans fatty acids (TFA), omega-6 …

Rationale: Chronic obstructive pulmonary disease (COPD) is variable in its development.
Lung microbiota and metabolites collectively may impact COPD pathophysiology, but …