Therapeutic potential of dental stem cells

EP Chalisserry, SY Nam, SH Park… - Journal of tissue …, 2017 - journals.sagepub.com
Stem cell biology has become an important field in regenerative medicine and tissue
engineering therapy since the discovery and characterization of mesenchymal stem cells …

Periodontal tissue engineering and regeneration: current approaches and expanding opportunities

FM Chen, Y Jin - Tissue Engineering Part B: Reviews, 2010 - liebertpub.com
The management of periodontal tissue defects that result from periodontitis represents a
medical and socioeconomic challenge. Concerted efforts have been and still are being …

Comparative analysis of in vitro osteo/odontogenic differentiation potential of human dental pulp stem cells (DPSCs) and stem cells from the apical papilla (SCAP)

A Bakopoulou, G Leyhausen, J Volk, A Tsiftsoglou… - Archives of oral …, 2011 - Elsevier
OBJECTIVE: The aim of this study was to compare the in vitro osteo/odontogenic
differentiation potential of mesenchymal stem cells (MSCs) derived from the dental pulp …

Stem cell-based biological tooth repair and regeneration

AA Volponi, Y Pang, PT Sharpe - Trends in cell biology, 2010 - cell.com
Teeth exhibit limited repair in response to damage, and dental pulp stem cells probably
provide a source of cells to replace those damaged and to facilitate repair. Stem cells in …

Porphyromonas gingivalis LPS inhibits osteoblastic differentiation and promotes pro-inflammatory cytokine production in human periodontal ligament stem cells

H Kato, Y Taguchi, K Tominaga, M Umeda… - Archives of oral …, 2014 - Elsevier
Objective Porphyromonas gingivalis (P. gingivalis) lipopolysaccharide (LPS) induces pro-
inflammatory cytokines, such as interleukin-1 β (IL-1β), IL-6, and IL-8, which induce …

Clinical utility of stem cells for periodontal regeneration

K Hynes, D Menicanin, S Gronthos… - Periodontology …, 2012 - Wiley Online Library
The aim of this review is to discuss the clinical utility of stem cells in periodontal regeneration
by reviewing relevant literature that assesses the periodontal‐regenerative potential of stem …

Enhancement of periodontal tissue regeneration by conditioned media from gingiva-derived or periodontal ligament-derived mesenchymal stem cells: a comparative …

J Qiu, X Wang, H Zhou, C Zhang, Y Wang… - Stem cell research & …, 2020 - Springer
Background Evidence has demonstrated conditioned medium (CM) from periodontal
ligament stem cells (PDLSCs) improved periodontal regeneration. Gingival mesenchymal …

Efficacy of stem cells on periodontal regeneration: systematic review of pre‐clinical studies

SA Tassi, NZ Sergio, MYO Misawa… - Journal of periodontal …, 2017 - Wiley Online Library
This systematic review aims to evaluate mesenchymal stem cells (MSC) periodontal
regenerative potential in animal models. MEDLINE, EMBASE and LILACS databases were …

Tissue engineered periodontal products

PM Bartold, S Gronthos, S Ivanovski… - Journal of …, 2016 - Wiley Online Library
Attainment of periodontal regeneration is a significant clinical goal in the management of
advanced periodontal defects arising from periodontitis. Over the past 30 years numerous …

High levels of β‐catenin signaling reduce osteogenic differentiation of stem cells in inflammatory microenvironments through inhibition of the noncanonical Wnt …

N Liu, S Shi, M Deng, L Tang, G Zhang… - Journal of Bone and …, 2011 - academic.oup.com
Periodontal ligament stem cells (PDLSCs), a new population of mesenchymal stem cells
(MSCs), have been isolated from the periodontal ligament (PDL). The capacity of …