Leptin is secreted by adipose tissue and regulates energy homeostasis, neuroendocrine
function, metabolism, immune function and other systems through its effects on the central …

Procreation is essential for survival of species. Not surprisingly, complex neuronal networks
have evolved to mediate the diverse internal and external environmental inputs that regulate …

Leptin is now considered an important signalling molecule of the reproductive system, as it
regulates the production of gonadotrophins, the blastocyst formation and implantation, the …

This article is part of a Special Issue “Puberty and Adolescence”. Reproduction is an energy-
demanding function. Accordingly, puberty is metabolically gated, as a means to prevent …

Albeit essential for perpetuation of species, reproduction is an energy-demanding function
that can be adjusted to body metabolic status. Reproductive maturation and function can be …

Reproductive function is dependent on energy resources. The role of weight, body
composition, fat distribution and the effect of diet have been largely investigated in …

Reproductive conditions secondary to disorders of the hypothalamic–pituitary–gonadal
(HPG) axis are common and are associated with important health implications and …

Leptin is an adipocyte-derived hormone involved in a myriad of physiological process,
including the control of energy balance and several neuroendocrine axes. Leptin-deficient …

Hypothalamic neuropeptide Y (NPY) and proopiomelanocortin (POMC) neurons act to
sense and coordinate the brain's responses to metabolic cues. One neuronal network that is …

Our understanding of kisspeptin and its actions depends, in part, on a detailed knowledge of
the neuroanatomy of the kisspeptin signaling system in the brain. In this chapter, we will …