iAtbP-Hyb-EnC: Prediction of antitubercular peptides via heterogeneous feature representation and genetic algorithm based ensemble learning model

S Akbar, A Ahmad, M Hayat, AU Rehman… - Computers in Biology …, 2021 - Elsevier
Tuberculosis (TB) is a worldwide illness caused by the bacteria Mycobacterium tuberculosis.
Owing to the high prevalence of multidrug-resistant tuberculosis, numerous traditional …

Antimicrobial peptides (AMPs): potential therapeutic strategy against trypanosomiases?

M Rojas-Pirela, U Kemmerling, W Quiñones… - Biomolecules, 2023 - mdpi.com
Trypanosomiases are a group of tropical diseases that have devastating health and socio-
economic effects worldwide. In humans, these diseases are caused by the pathogenic …

Immunoinformatics studies and design of a potential multi-epitope peptide vaccine to combat the fatal visceral leishmaniasis

OS Onile, F Musaigwa, N Ayawei, V Omoboyede… - Vaccines, 2022 - mdpi.com
Leishmaniasis is a neglected tropical disease caused by parasitic intracellular protozoa of
the genus Leishmania. The visceral form of this disease caused by Leishmania donovani …

Humanizing plant-derived snakins and their encrypted antimicrobial peptides

Z Ghanbarzadeh, S Hemmati, A Mohagheghzadeh - Biochimie, 2022 - Elsevier
Due to safety restrictions, plant-derived antimicrobial peptides (AMPs) need optimization to
be consumed beyond preservatives. Herein, 175 GASA-domain-containing snakins were …

[PDF][PDF] Antimicrobial Peptides (AMPs): Potential Therapeutic Strategy against Trypanosomiases? Biomolecules 2023, 13, 599

M Rojas-Pirela, U Kemmerling, W Quinones… - 2023 - academia.edu
Trypanosomiases are a group of tropical diseases that have devastating health and
socioeconomic effects worldwide. In humans, these diseases are caused by the pathogenic …

[PDF][PDF] The Study of the Binding Ability of Antimicrobial Peptides to Spike Protein of the Coronavirus by Docking and Molecular Dynamics Simulation

M Sara, Z Mahboobeh - 2024 - jhbmi.ir
Results: The obtained results from molecular dynamics examine the stability of complex
structure and energy calculations. RMSD, RMSF, radius of gyration, and SASA analyses …

[PDF][PDF] Immunoinformatics Studies and Design of a Potential Multi-Epitope Peptide Vaccine to Combat the Fatal Visceral Leishmaniasis. Vaccines 2022, 10, 1598

OS Onile, F Musaigwa, N Ayawei, V Omoboyede… - 2022 - researchgate.net
Leishmaniasis is a neglected tropical disease caused by parasitic intracellular protozoa of
the genus Leishmania. The visceral form of this disease caused by Leishmania donovani …

بررسی قابلیت اتصال پپتیدهای ضدمیکروبی به پروتئینspike ویروس کرونا با روش داکینگ و شبیه‌سازی دینامیک مولکولی

مرتضی علی, ضرابی - مجله انفورماتیک سلامت و زیست پزشکی, 2024‎ - jhbmi.ir
مقدمه: از زمان شروع سال 2020، SARS-CoV-2 به طور قابل توجهی باعث بیماری تعداد زیادی از افراد
شده و تحقیقات گسترده ‌ای را به سوی خود جلب کرده است. پپتیدهای ضد میکروبی به دلیل ایمنی …

Structural and biophysical characterization of the interaction between Schistosoma mansoni axonemal dynein intermediate chain protein and dynarrestin

D Pillay - 2022 - ujcontent.uj.ac.za
Praziquantel (PZQ) has been the World Health Organizations (WHO) recommended
schistosomiasis treatment for the greater part of 5 decades. PZQ resistant Schistosoma spp …