Noncoding RNA therapeutics—challenges and potential solutions
Therapeutic targeting of noncoding RNAs (ncRNAs), such as microRNAs (miRNAs) and
long noncoding RNAs (lncRNAs), represents an attractive approach for the treatment of …
long noncoding RNAs (lncRNAs), represents an attractive approach for the treatment of …
A review of computational drug repositioning: strategies, approaches, opportunities, challenges, and directions
Drug repositioning is the process of identifying novel therapeutic potentials for existing drugs
and discovering therapies for untreated diseases. Drug repositioning, therefore, plays an …
and discovering therapies for untreated diseases. Drug repositioning, therefore, plays an …
Trends in the development of miRNA bioinformatics tools
L Chen, L Heikkinen, C Wang, Y Yang… - Briefings in …, 2019 - academic.oup.com
MicroRNAs (miRNAs) are small noncoding RNAs that regulate gene expression via
recognition of cognate sequences and interference of transcriptional, translational or …
recognition of cognate sequences and interference of transcriptional, translational or …
Non-coding RNAs in human health and disease: potential function as biomarkers and therapeutic targets
T Loganathan, GP Doss C - Functional & integrative genomics, 2023 - Springer
Human diseases have been a critical threat from the beginning of human history. Knowing
the origin, course of action and treatment of any disease state is essential. A microscopic …
the origin, course of action and treatment of any disease state is essential. A microscopic …
EVmiRNA: a database of miRNA profiling in extracellular vesicles
Extracellular vesicles (EVs), such as exosomes and microvesicles, acted as cell-to-cell
communication vectors and potential biomarkers for diseases. microRNAs (miRNAs) are the …
communication vectors and potential biomarkers for diseases. microRNAs (miRNAs) are the …
RNAInter in 2020: RNA interactome repository with increased coverage and annotation
Research on RNA-associated interactions has exploded in recent years, and increasing
numbers of studies are not limited to RNA–RNA and RNA–protein interactions but also …
numbers of studies are not limited to RNA–RNA and RNA–protein interactions but also …
A survey of current trends in computational drug repositioning
Computational drug repositioning or repurposing is a promising and efficient tool for
discovering new uses from existing drugs and holds the great potential for precision …
discovering new uses from existing drugs and holds the great potential for precision …
miRNet-dissecting miRNA-target interactions and functional associations through network-based visual analysis
Y Fan, K Siklenka, SK Arora, P Ribeiro… - Nucleic acids …, 2016 - academic.oup.com
MicroRNAs (miRNAs) can regulate nearly all biological processes and their dysregulation is
implicated in various complex diseases and pathological conditions. Recent years have …
implicated in various complex diseases and pathological conditions. Recent years have …
HMDD v2. 0: a database for experimentally supported human microRNA and disease associations
Abstract The Human microRNA Disease Database (HMDD; available via the Web site at
http://cmbi. bjmu. edu. cn/hmdd and http://202.38. 126.151/hmdd/tools/hmdd2. html) is a …
http://cmbi. bjmu. edu. cn/hmdd and http://202.38. 126.151/hmdd/tools/hmdd2. html) is a …
MicroRNA regulatory network analysis using miRNet 2.0
MicroRNAs exert their effects in the context of gene regulatory networks. The recent
development of high-throughput experimental approaches and the growing availability of …
development of high-throughput experimental approaches and the growing availability of …