Despite developing prenatally, the adipose tissue is unique in its ability to undergo drastic
growth even after reaching its mature size. This development and subsequent maintenance …

Simple Summary Adipose tissue is considered a metabolic organ that adjusts overall energy
homeostasis and critical hormones to the body's needs. In conditions of caloric intake …

Summary Mammalian SWI/SNF (mSWI/SNF or BAF) ATP-dependent chromatin remodeling
complexes play critical roles in governing genomic architecture and gene expression and …

The relevance of extracellular matrix (ECM) remodeling is reported in white adipose tissue
(AT) and obesity-related dysfunctions, but little is known about the importance of ECM …

Bile acids act as signalling molecules that contribute to maintenance of energy homeostasis
in mice and humans. Activation of G-protein-coupled bile acid receptor TGR5 induces …

Engineered beige adipose tissues could be used for screening therapeutic strategies or as a
direct treatment for obesity and metabolic disease. Microvascular fragments are vessel …

Available transcriptomes of the mammalian kidney provide limited information on the spatial
interplay between different functional nephron structures due to the required dissociation of …

Laminins are extracellular matrix proteins that reside in the basement membrane and
provide structural support in addition to promoting cellular adhesion and migration. Through …

Brown adipose tissue (BAT) is a key thermogenic organ whose expression of uncoupling
protein 1 (UCP1) and ability to maintain body temperature in response to acute cold …

Obesity and its associated comorbidities place a substantial burden on public health. Given
the considerable potential of brown adipose tissue in addressing metabolic disorders that …