Causes and consequences of RNA polymerase II stalling during transcript elongation
M Noe Gonzalez, D Blears, JQ Svejstrup - Nature reviews Molecular …, 2021 - nature.com
The journey of RNA polymerase II (Pol II) as it transcribes a gene is anything but a smooth
ride. Transcript elongation is discontinuous and can be perturbed by intrinsic regulatory …
ride. Transcript elongation is discontinuous and can be perturbed by intrinsic regulatory …
Pre-clinical study evaluating novel protein phosphatase 2A activators as therapeutics for neuroblastoma
LV Bownes, R Marayati, CH Quinn, AM Beierle… - Cancers, 2022 - mdpi.com
Simple Summary Despite significant advancements in neuroblastoma therapy, over half of
the children with high-risk neuroblastoma will suffer disease relapse. Protein phosphatase …
the children with high-risk neuroblastoma will suffer disease relapse. Protein phosphatase …
Advancements in chemical biology targeting the kinases and phosphatases of RNA polymerase II-mediated transcription
Phosphorylation of RNA polymerase II (RNAP II) coordinates the temporal progression of
eukaryotic transcription. The development and application of chemical genetic methods …
eukaryotic transcription. The development and application of chemical genetic methods …